HEMA-chitosan polymer.Figure 4.8 N,N’-Carbonyldiimidazole and its methacrylic acid derivative.Figure 4.9 Cyclosporine A.Figure 4.10 Disodium cromoglycate.Figure 4.11 Disuccinimidyl carbonate.Figure 4.12 Biotin.Figure 4.13 Tobramycin.Figure 4.14 Vancomycin.Figure 4.15 Amount of drug release vs. time (64).Figure 4.16 Diazeniumdiolate.Figure 4.17 Acetazolamide.Figure 4.18 Flurbiprofen.Figure 4.19 Timolol.Figure 4.20 Change of drug release rate vs. Vitamin E concentration (107).Figure 4.21 Dexamethasone.Figure 4.22 Trisodium citrate.Figure 4.23 Ketotifen fumarate.Figure 4.24 Ketotifen fumarate in the tear fluid as a function of time (133).Figure 4.25 Cumulative release of ketotifen fumarate (95).Figure 4.26 Ciprofloxacin.Figure 4.27 3-Methacryloxypropyltris(trimethylsiloxy) silane.Figure 4.28 Antibacterial ocular drugs.Figure 4.29 4-Methyl-4-pentenoic acid.Figure 4.30 In-vitro release as a function of time (141).Figure 4.31 Polymyxin B.Figure 4.32 Vancomycin.Figure 4.33 Epinastine.Figure 4.34 Bimatoprost.Figure 4.35 Dipicolylamine.Figure 4.36 Gatifloxacin.Figure 4.37 Dorzolamide.Figure 4.38 Ethoxzolamide.Figure 4.39 Monomers for hydrogels.Figure 4.40 L-Histidine.Figure 4.41 Hyaluronic acid.Figure 4.42 Compounds used in Preparation 4–4.Figure 4.43 Cumulative release of hyaluronic acid (90).Figure 4.44 Preparation of the ring-implanted contact lenses, reprinted from Mac...Figure 4.45 Lifitegrast (N-[[2-(6-Benzofuranylcarbonyl)-5,7-dichloro-1,2,3,4-tet...Figure 4.46 Diclofenac sodium.Figure 4.47 Release of diclofenac sodium vs. (M/T) ratio (161).Figure 4.48 Cetalkonium chloride.Figure 4.49 Moxifloxacin.Figure 4.50 N-[Tris(trimethylsiloxy)silylpropyl]acrylamide.Figure 4.51 Norfloxacin.Figure 4.52 Sparfloxacin.Figure 4.53 Latanoprost.Figure 4.54 Loteprednol etabonate.Figure 4.55 Template molecules.5 Chapter 5Figure 5.1 Oxamic acid.Figure 5.2 Average corneal swelling vs. time (19).Figure 5.3 Thimerosal.Figure 5.4 Poly(hexamethylene) biguanide.Figure 5.5 Compounds for eye drops.Figure 5.6 Denatonium benzoate.Figure 5.7 N-Vinyl-2-pyrrolidone and Vinylimidazolium methochloride.Figure 5.8 Saccharides (46).Figure 5.8 (cont) Saccharides (46).Figure 5.9 Chelating agents.Figure 5.10 Preservatives.Figure 5.11 Hexamethylene biguanide.Figure 5.12 5-Bromo-2’-deoxyuridine.Figure 5.13 Hematoxylin.Figure 5.14 Compounds for derivatizing.Figure 5.15 Diquafosol.Figure 5.16 Refractive error change with time (90, 97).
List of Tables
1 Chapter 1Table 1.1 History of contact lenses (2).Table 1.2 Monomers for contact lenses.Table 1.3 Monomers (18).Table 1.4 Side-chain-linked amino acids (18).Table 1.5 Hydrophilic methacrylamide-based monomers (23).Table 1.6 Hydrophilic polymers (23).Table 1.7 Multifunctional monomers (23).Table 1.8 Monomers (19).Table 1.9 Mechanical properties (19).Table 1.10 Monomers (26).Table 1.11 Initiators (26).Table 1.12 Azlactone monomers (28).Table 1.13 Monomers for controlling water content (30).Table 1.14 Nucleating agents (31).Table 1.15 Crosslinking agents (39).Table 1.16 Monomers (43).Table 1.17 Poly(siloxane) monomers (43).Table 1.18 Target biomarkers (52).Table 1.19 Examples of target analytes (61).Table 1.20 Common species in tears and blood (61).Table 1.21 Glucose biosensors developed for contact lenses (66).Table 1.22 UV-blocking agents (21).Table 1.23 Silicone monomers (21).Table 1.24 Composition for a multifocal contact lens (21).Table 1.25 Monomers for non-silicone hydrogels (31).Table 1.26 Crosslinking agents for non-silicone hydrogels (31).Table 1.27 Free radical catalysts and initiators (31).Table 1.28 Initiators.Table 1.29 Contents of the contact lenses (125).Table 1.30 Free radical generating initiators (126).Table 1.31 Synthesis and properties of polymers.Table 1.32 Monomers (127).Table 1.33 Isocyanates (127).Table 1.34 Protein absorption of artificial tear fluid on the surface of sample ...Table 1.35 Number of colony-forming units (141).
2 Chapter 2Table 2.1 Optical design software.Table 2.2 Inks and pigment levels (13).Table 2.3 Formulation of contact lens (25).Table 2.4 Polymers for mat production (27).Table 2.5 Comonomers for mat production (27).Table 2.6 Hydrophilic monomers (31).Table 2.7 Formulation for preparing contact lenses (40).
3 Chapter 3Table 3.1 Standards for testing contact lenses.Table 3.2 Potential uses of contact lenses (44).Table 3.3 Pluronic® surfactants (55).Table 3.4 Cleaning composition for contact lenses (55).Table 3.5 Daily disposable lenses (73).Table 3.6 Roughness values (91).
4 Chapter 4Table 4.1 Setschenow constants.Table 4.2 Drugs for molecularly imprinted contact lenses (68).Table 4.3 monomer mixture for silicone contact lenses (130, 132).Table 4.4 Formulations of the contact lenses (95).Table 4.5 Loss of drugs (132).
5 Chapter 5Table 5.1 Eye diseases.Table 5.2 Properties of the lenses (19).Table 5.3 Saccharides (45).Table 5.4 Chelating agents (45).Table 5.5 Results of dry-eye study (89).
Guide
1 Cover
4 Preface
6 Index
Pages
1 v
2 ii
3 iii
4 iv
5 xi
6 xii
7 xiii
8 1
9 2
10 3
11 4
12 5
13 6
