Cover image: Specter of death waiting over Panama (U. J. Keppler, 1904). Cover illustration for Puck, a political satire and humor magazine. (See Figure 1 in chapter 1.) (Courtesy of Beinecke Rare Book and Manuscript Library, Yale University.)
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Library of Congress Cataloging-in-Publication Data
Booss, John.
To catch a virus / John Booss, Marilyn J. August.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-1-55581-507-3 (pbk. : alk. paper)
I. August, Marilyn J. II. American Society for Microbiology. III. Title.
[DNLM: 1. Virology—history. 2. History, 19th Century. 3. History, 20th Century.
4. History, 21st Century. 5. Virology—methods. 6. Virus Diseases—diagnosis.
7. Virus Diseases—history. QW 11.1]
616.9′101—dc23
2012035227
eISBN: 978-1-68367-352-1
10 9 8 7 6 5 4 3 2 1
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In tribute to Gueh-Djen (Edith) Hsiung, PhD, who is remembered for her pioneering contributions to the field of diagnostic virology, for training and inspiring generations of diagnostic virologists with her passion for virology, and for her social grace and generosity. (Courtesy of Zhe Zhao.)
Contents
Chapter 1 Fear or Terror on Every Countenance: Yellow Fever
Chapter 2 Of Mice and Men: Animal Models of Viral Infection
Chapter 3 Filling the Churchyard with Corpses: Smallpox and the Immune Response
Chapter 4 What Can Be Seen: from Viral Inclusion Bodies to Electron Microscopy
Chapter 5 The Turning Point: Cytopathic Effect in Tissue Culture
Chapter 6 A Torrent of Viral Isolates: the Early Years of Diagnostic Virology
Chapter 7 Imaging Viruses and Tagging Their Antigens
Chapter 8 Immunological Memory: Ingenuity and Serendipity
Chapter 9 To the Barricades: the Molecular Revolution
List of Illustrations
Chapter 1
