of the measures hitherto employed to arrest the scourge?
And, on the other hand, is it not most afflicting to see discoveries of indisputable value buried out of view, submerged in public libraries, utterly unknown and forgotten, like their authors, to such a degree, that the distemper which they have made known in its entirety, and which is as old as the world itself, seems to us almost new in 1865?
God send, that these cruel trials and severe lessons which the past has bequeathed to us may teach us something for our benefit! May the irresistible might which is derived from the auspicious union of capital and intelligence supersede the vain and flimsy efforts of isolated energy! May the government, which lavishes hundreds of millions upon the destructive engines of war, devote some portion of its ample means to the study of hereditary infections and contagious diseases! For these fatal epidemics decimate men as well as cattle, and we may at least ward off from our children the desolating disease which at present afflicts ourselves.
We possess already every requisite means to protect ourselves from the formidable visitation of these diseases: we have science; we have the men who cultivate and teach it; we have the experience of the past added to our own. To-day, we are called upon to resist the baleful effects of cattle typhus; but another epizootia may come to-morrow, and strike our horses and our sheep – those domestic animals which constitute our most precious possession. The cholera hovers about us. If we do nothing, if we talk and debate instead of acting, these scourges will come upon us on a sudden, and find us quite as helpless as ever to resist their sway.
These palpable truths deserve to be further developed, and will be treated more copiously at the end of this book. They will constitute the complement of our work, necessarily written in haste, since the danger we had to expose was itself so urgent and alarming.
SECOND PART
This Part is divided, as already stated, into four chapters.
CHAPTER I
By following the example of those authors who have described the contagious typhus of the ox, we might proceed at once to explain its symptoms, and go directly to our purpose; but, by taking this hasty course, we should expose ourselves to be imperfectly understood by the majority of our readers, and to leave certain doubts in the minds of physicians as to the nature of the disease and the propriety of its treatment.
All animals, including man himself, are born with a predisposition and liability to contract a certain number of contagious febrile diseases; they bear in a manner a certain number of physiological elements, which might be called latent germs, and which, under given conditions, become the leaven of these diseases. This must, indeed, be the case, since after these disorders have been once developed those who have been cured of them are not apt to contract them again, the morbid developments having destroyed that natural aptitude which had previously existed to undergo the morbid action of the contagious virus. These diseases are not numerous; they constitute a very distinct class, and the same laws, which regulate the phenomena in one of them are applicable to all the rest.
These diseases exhibit the following characteristics: 1st, a period of incubation, during which the whole economy, more particularly the blood and humours, experience very important changes and modifications; 2nd, a febrile state, which varies in its continuous or intermittent types, and in its intensity, according to the species of the animals, and which proceeds from the alteration of the blood; 3rd, a revulsion at once toxical and congestive towards the nervous centre, inducing stupor; 4th, a flux of mucus from the mouth and chest; 5th, a more intense, congestive, and inflammatory flux or discharge from the external or internal teguments – the skin or the mucous membrane of the digestive channels; 6th, a period of adynamia and dejection, with a tendency, in some cases, to a critical or salutary rejection of the morbid matter by the development of tumours or abscesses in the skin; 7th, they are at once infectious and contagious, epizootic or epidemic; that is to say, they are transmitted in different degrees by contact, by inoculation, and at a distance by the means of vitiated air; 8th, finally – and this is their leading characteristic —they are not subject to recurrence, each individual that has once been affected, losing in general all aptitude to contract the disease a second time.
This last characteristic, when well understood, ought in reason to induce us to have recourse to the preventive treatment, and such has been the case with respect to the most virulent amongst them – small-pox and the typhus of the ox.
Prompted by these principles, which are as logical and fixed as any mathematical deduction, I suggested in 1855 that inoculation should be applied in typhoid fever, which is nothing else but the equivalent of intestinal small-pox, in order to prevent the disease in men. But if the simplest truth sometimes requires a contest of ages before it is heard and understood, I could not hope to fix attention on a fact which might be taken as problematical. I felt that I was outrunning time, and that I should neither be heard nor understood; and so it has proved.
Be that as it may, these typhous diseases have, as is seen, their laws and foreseen development. They attack animals generally, but chiefly herbivorous animals, endowed, as we have shown in the first part, with a vital resistance which is, relatively speaking, very inconsiderable.
These febrile typhous diseases (whether their development is caused by a spontaneous morbid action in the patient or by an evident contagion), have a period of incubation during which the vital strength undergoes latent morbid modifications, though not sufficient to indicate, save in times of epizootics and epidemics, the particular form which is about to reveal its symptoms in the course of a few days. This period of incubation being over, the mouth and chest become affected, and fever declares itself; and then the materies morbi, which is to become the special and dominant characteristic of the distemper, is directed either to the skin, or to the digestive mucous membrane. In the first case, we see evidence of exanthematic diseases, which present only the lightest forms of detersive disorders, such as measles, scarlatina, or that more serious one, from its pustulous form, the small-pox. In the second case, the elimination takes place from the intestinal canal, and then we see produced in animals, as well as in men, the typhous diseases: that is to say, the typhoid fever – a pustulous and ulcerous malady of the intestines – or the common typhus of the hospitals, prisons, and campaigning armies; and again, in animals, there is also the typhus of the steppes, of the marshes, &c.
The Eastern pestilence, the plague of Rome in the age of Antoninus and the plague of Athens, which might have given to Hippocrates the right of treating with Artaxerxes as one potentate treats with another, ought perhaps to be classed among those typhuses not subject to recurrence.
As for the cholera, it seems to be a contagious and epidemic disorder, of a distinct and particular kind. We are ignorant of its essential cause, its nature, and its mode of treatment; and although it has prevailed in every age, and even frequently of late years, it will always, by reason of the strange formation of our medical institutions, find us as weak and defenceless to resist its attack as we have ever been.
If we have been properly understood, typhous diseases are, above all, general febrile affections. At one time the materies morbi, or discharge, affects the skin; at another, the digestive mucous membrane. When it acts upon the skin, as clinical observation shows, there is sometimes a sort of hesitation in the eruptive process; people wonder what disease is coming forth; the eruption wavers in the form it will assume, till at length its real character is determined. The same uncertainty prevails when the intestines are affected. Sometimes the exanthema is merely the equivalent of simple measles or scarlatina of the intestinal mucous membrane, and many typhoid fevers of short continuance are nothing else in their nature. The same occurs in common typhuses. Sometimes the local affection proceeds as far as pustulous eruption, sometimes only to exanthematic rubefaction; hence the various alterations which we have witnessed in the intestines of cattle killed in our presence at the slaughter-houses
