Twenty female patients on 500- to 550- kcal diets receiving daily injections of 125 IU of human chorionic gonadotrophin (hCG) were compared with 20 female patients on 500- to 550-kcal diets receiving placebo injections. Patients in both groups were instructed to return for daily injections 6 days each week for a total of 36 injections (unless desired weight was achieved prior to this). The hCG group lost significantly more mean weight, had a significantly greater mean weight loss per injection, and lost a significantly greater mean percentage of their starting weight. The percentage of affirmative daily patient responses indicating "little or no hunger" and "feeling good to excellent" was significantly greater in the HCG group than in the placebo group. Additional investigation of the influence of hCG on weight loss, hunger, and well-being seems indicated.
American Journal of Clinical Nutrition, Vol. 26, 211-218, Copyright © 1973 by the American Society for Clinical Nutrition, Inc.
| Revised 800 calorieProtocol LCD | “Original” Dr. Simeons Protocol VLCD |
| 550-800 calories daily – LCD - Low Calorie Diet | 500 calories daily – VLCD - Very Low Calorie Diet |
| Eat breakfast to include 1 protein and fruit serving | No breakfast (optional fruit serving only) |
| Effectively an LCD; is safer than the original | Effectively a VLCD mandating closer supervision |
| More selection of green vegetables, higher protein content and additional fruit serving | Limited food choices |
| Multi-vitamin/minerals highly suggested | No vitamins except calcium |
| Take all medications prescribed by your MD | Suggested to stop all medications |
| hCG available in sublingual form and sub-Q injectable | Dr. Simeons gave his patients only intramuscular injections |
| Detailed hCG Diet Book that is an exceptional educational tool | Hard to understand pamphlet “Pounds and Inches” written 50 years ago, very confusing to most |
| Updated Phase 3 that ensures a successful stabilization | Phase 3 is vague and confusing to most |
| Recipes for Phases 2-3 meals | Limited list of food to prepare |
| Products in protocol are easy to find at stores | Some products are difficult to find at stores. |
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