Sep;86(9):4139-46.
16.Aleman A. et al. Insulin-Like Growth Factor-I and Cognitive Function in Healthy Older Men J Clin Endocrinol Metab 84:471475, 1999.
17.Sugimoto T et al. Effect of recombinant human growth hormone in elderly osteoporotic women. Clin Endocrinol (Oxf) 1999 Dec;51(6):715-724.
18.Napoli R et al. J Am Coll Cardiol 2002 Jan 2;39(1):90-5.
19.Johannsson G et al. GH treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism and reduces diastolic BP. J Clin Endocinol Metab 1997;82:727-734.
20.Albert SG et al. Low-dose recombinant human growth hormone as adjuvant therapy to lifestyle modifications in the management of obesity. Clin Endocrinol Metab. 2004 Feb;89(2):695-701.
21.Nam SY et al. Low-dose growth hormone treatment combined with diet restriction decreases insulin resistance by reducing visceral fat and increasing muscle mass in obese type 2 diabetic patients.
22.Paragraph excerpted from Rothenberg R, et al. “Hormone Optimization: Evidence Based Practical Management.” In Encyclopedia of Clinical Anti-Aging Medicine & Regenerative Biomedical Technologies, A4M, 2012, pp. 281-342.
23.Besson A et al. Reduced longevity in untreated patients with isolated growth hormone deficiency. J Clin Endocrinol Metab. 2003 Aug; 88(8):3664-7.
24.Ruiz-Torres A. and Soares de Melo Kirzner M. “Ageing and Longevity Are Related to Growth Hormone/Insulun-Like Growth Factor-1 Secretion.” Gerontology 2002; 48:401-407.
25.Stochholm, K et al. Mortality and GH Deficiency a Nationwide Study. European Journal of Endocrinology. (2007)157 9-18
26.The Journals of Gerontology:Series A, Vol. 67A, Issue 6; June 2012; http://biomedgerontology.oxfordjournals.org/content/67A/6.toc
27.Yusuke Higashi, Sergiy Sukhanov, Asif Anwar, Shaw-Yung Shai, Patrice Delafontaine. “Aging, Atherosclerosis, and IGF-1.” J Gerontol A Biol Sci Med Sci (2012) 67A (6): 626-639.
28.Zoltan Ungvari and Anna Csiszar. “The Emerging Role of IGF-1 Deficiency in Cardiovascular Aging: Recent Advances.” J Gerontol A Biol Sci Med Sci (2012) 67A (6): 599-610.
29.Yancy CW, Jessup M, Bozkurt B, Masoudi FA, et al; ACCF/AHA Task Force Members. “2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.” J Am Coll Cardiol. 2013 Jun 5.
30.Savine R. et al. Growth hormone replacement for the somatopause. Horm Res 2000;53 Suppl 3:37-4
31.Wuster C, Melchinger U, Eversmann T, Hensen J, Kann P, von zur Muhlen A, Ranke MB, Schmeil H, Steinkamp H, Tuschy U. Reduced incidence of side-effects of growth hormone substitution in 404 patients with hypophyseal insufficiency. Results of a multicenter indications Study. Med Klin 1998 Oct 15;93(10):585-91.
32.Ingermann AR, Yang YF, Han J, Mikami A, Garza AE, Mohanraj L, Fan L, Idowu M, Ware JL, Kim HS, Lee DY, Oh Y. Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer. J Biol Chem. 2010 Sep 24;285(39):30233-46.
33.Scirè G, Del Bianco C, Spadoni GL, Cianfarani S. Growth hormone therapy does not alter the insulin-like growth factor-I/insulin-like growth factor binding protein-3 molar ratio in growth hormone-deficient children. J Endocrinol Invest. 2008 Feb;31(2):153-8.
34.Jenkins PJ, Mukherjee A, Shalet SM. Does growth hormone cause cancer? Clin Endocrinol (Oxf). 2006 Feb;64(2):115-21.
35.Molitch ME. Diagnosis of GH deficiency in adults--how good do the criteria need to be? J Clin Endocrinol Metab. 2002 Feb;87(2):473-6.
36.Svensson J, et al. J Clin Endocrinol Metab. 2004;89(7):3306-12.
37.Eiser C, et al. Growth Hormone Treatment and Quality of Life among Survivors of Childhood Cancer. Horm Res. 2005; 633(6):300-4.
38.Zumkeller W, et al. _Expression and synthesis of insulin-like growth factor-binding proteins in human glioma cell lines. Int J Oncol. 1998 Jan;12(1)129-35.
39.Gielen SC, et al. Steroid-modulated proliferation of human endometrial carcinoma cell lines: any role for insulin-like growth factor signaling? J Soc Gynecol Investig. 2005 Jan;12(1):58-64.
40.Bach LA, Headey SJ, Norton RS. IGF-binding proteins the pieces are falling into place. Trends Endocrinol Metab. 2005 July;16(5):228-34.
41.Swerdlow AJ, et al. J Clin Endocrinol Metab 2000;85(12):4444-9.
42.Tacke J, et al. JPEN J Parenter Enteral Nutr 2000;24(3):140-4.
43.Critical Evaluation of the Safety of Recombinant GH Administration: Statement from the Growth Hormone Research Society, J Clin Endo Metab, May 2001.
44.Gardner et al. "Effects of dietary carbohydrate on fasting levels of human growth hormone and cortisol," Proceedings of the Soc for Exper Biol and Med, 1982, 36-40.
45.US District Court, District of Nevada Case #3:06-CR-147-BES-VPC, USA vs. James W. Forsythe.
46.Interview with James Forsythe, M.D., HMD, 18 September 2013.
47.Morales AJ, Nolan JJ, Nelson JC, Yen SS. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab. 1994;78:1360-1367. Erratum in: J Clin Endocrinol Metab 1995;80:2799.
48.Rabijewski M, Zgliczyński W. Positive effects of DHEA therapy on insulin resistance and lipids in men with angiographically verified coronary heart disease--preliminary study]. Endokrynol Pol. 2005 Nov-Dec;56(6):904-10.
49.Baulieu E.E., Thomas G., Legrain S., Lahlou N., Roger M., Debuire B., Faucounau V., Girard L., Hervy M.P., Latour F., Leaud M.C., Mokrane A., Pitti-Ferrandi H., Trivalle C., de Lacharriere O., Nouveau S., Rakoto-Arison B., Souberbielle J.C., Raison J., Le Bouc Y., Raynaud A., Girerd X., Forette F. (2000). Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci USA, 97(8):4279–4284.
50.Baulieu E.E. (1996). Dehydroepiandrosterone (DHEA): a fountain of youth? J Clin Endocrinol Metabo, 81:3147–3151.
51.Stuckelberger A. (2008). Anti-Ageing Medicine : Myths and Chances. ETH Verlag, Zurich, Switzerland. e-book in open access: http://www.vdf.ethz.ch/service/3225/9783728132253_anti-ageing-medicine_oa.pdf
52.Daniel M Kelly and T Hugh Jones. “Testosterone: a vascular hormone in health and disease,” J Endocrology 217:3 R47–R71.
53.Pugh PJ, Jones RD, West JN, Jones TH, Channer KS. Testosterone treatment for men with chronic heart failure. Heart. 2004 Apr;90(4):446-7.
54.Malkin CJ et al. The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men J Clin Endocrinol Metab. 2004 Jul; 89(7):3313-8.
55.Turhan S et al. The association between androgen levels and premature coronary artery disease in men. Coron Artery Dis. 2007 May; 18(3):159-62.
56.Rosano
