style="font-size:15px;"> “It’s not that,” she said. “It’s...something I can’t explain.”
“It’s because you’re an Eliot, isn’t it?” I asked, resentfully. “You feel that you can’t marry for the same reasons that Gideon Sargent felt that he couldn’t. You don’t have a trace of the Innsmouth look about you, but you have the dreams, don’t you? You nearly admitted as much to Gideon, that night when he came to the hotel.”
“Yes,” she said, faintly. “I have the dreams. But I’m not like those poor old mad people who locked themselves away until you came. I know that you won’t find a cure for them, even if you can find an explanation. I understand well enough what can come of your research and what can’t.”
“I’m not sure that you do,” I told her. “In fact, I’m not sure that you understand your own condition. Given that you don’t have a trace of the look, and given that you’re not directly descended from any of the Eliots of Innsmouth, what makes you think that your nightmares are anything more than just that: nightmares? As you said to Gideon when he raised the issue, everyone has dreams. Even I have dreams.” In the circumstances, I nearly said had, but that would have been too obvious a whine.
“You’re a biochemist,” she said. “You think that the physical malformation is the real issue, and that the dreams are peripheral. Innsmouthers don’t see it that way—for them, the dreams are the most important thing, and they’ve always seen the look as an effect rather than a cause. I’m an Innsmouther too.”
“But you’re a educated woman! You may be a historian, but you know enough science to know what the Innsmouth look really is. It’s a genetic disorder.”
“I know that the Esoteric Order of Dagon’s beliefs and Obed Marsh’s adventures in the South Seas are just myths,” she agreed. “They’re stories concocted, as you said to Gideon, to explain and excuse an inexplicable affliction caused by defective genes. But it might as easily have been the Eliots who imported those genes as anyone else, and they might easily have been in the family for many generations—England used to have its inbred populations too, you know. I know that you only took tissue-samples from me for what you called purposes of comparison, but I’ve been expecting all along that you would come to me and tell me that you’d found the rogue gene responsible for the Innsmouth look, and that I have it too.”
“It doesn’t matter,” I said, plaintively. “It really doesn’t matter. We could still get married.”
“It matters to me,” she said. “And we can’t.”
* * * *
I suppose that incident with Ann should have redoubled my determination to trace the DNA-complex that was responsible for the Innsmouth syndrome, in order to enable me to prove to her that she wasn’t afflicted, and that her dreams were only dreams. In fact, it didn’t; I was hurt by her rejection, and depressed. I continued to work as hard as I ever had, but I found it increasingly difficult to go to Innsmouth, to stay in the hotel where she lived, and to walk through the streets which she owned.
I began to look for someone else to soothe my emotional bruises, while Ann and I drifted steadily apart. We were no longer good friends in any real sense, though we kept up some kind of a pretense whenever we met.
In the meantime, the members of my experimental sample continued to die. I lost three more in the second year, and it became even more obvious that whatever I discovered wasn’t going to be of any practical import to the people whose DNA I was looking at. In a way, it didn’t matter that much to the program—the DNA that Gideon and all the rest had provided still existed, carefully frozen and stored away. The project was still healthy, still making headway.
In the third year, I finally found what I was looking for: an inversion on the seventh chromosome, which had trapped seven genes, including three oddballs. In homozygotes like Gideon, the genes paired up and were expressed in the normal way; in heterozygotes, like most of my sample—including all of the survivors—the chromosomes could only pair up if one of them became looped around, stopping several of the genes from functioning. I didn’t know what all of the genes did, or how—but my biochemical analyses had given me a partial answer.
I drove to Innsmouth the next day, in order to tell Ann the news. Although our relationship had soured and fallen apart, I still owed her as much of an explanation as I could now give.
“Do you know what Haeckel’s law is?” I asked her, while we walked beside the Manuxet, past the place where the Marsh refinery had once been located.
“Sure,” she said. “I read up on the whole thing, you know, after we got involved. Haeckel’s law says that ontogeny recapitulates phylogeny—that the embryo, in developing, goes through a series of stages which preserve a kind of memory of the evolutionary history of an organism. It’s been discredited, except as a very loose metaphor. I always thought that the Innsmouth look might turn out to have something to do with the fact that the human embryo goes through a stage where it develops gills.”
“Only the ghosts of gills,” I told her. “You see, the same embryonic structures that produce gills in fish produce different structures in other organisms; it’s called homology. Conventional thinking, muddied by the fact that we don’t really understand the business of blueprinting for physical structure, supposes that when natural selection works to alter a structure into its homologue—as when the fins of certain fish were modified by degrees into the legs of amphibians, for instance, or the forelimbs of certain lizards became the wings of birds—the blueprint genes for the new structure replace the blueprint genes for the old. But that’s not the only way it could happen. It may be that the new genes arise at different loci from the old ones, and that the old ones are simply switched off. Because they aren’t expressed any more in mature organisms they’re no longer subject to eliminative natural selection, so they aren’t lost, and even though they’re bound to be corrupted by the accumulation of random mutations—which similarly aren’t subject to elimination by natural selection—they remain within the bodies of descendant species for millions of years. If so, they may sometimes be expressed, if there’s a genetic accident of some kind that prevents their being switched off in a particular organism.”
She thought about it for a few moments, and then she said: “What you’re saying is that human beings—and, for that matter, all mammals, reptiles and amphibians—may be carrying around some of the blueprint genes for making fish. These are normally dormant—untroublesome passengers in the body—but under certain circumstances, the switching mechanism fails and they begin to make the body they’re in fishy.”
“That’s right,” I said. “And that’s what I shall propose as the cause of the Innsmouth syndrome. Sometimes, as with Gideon, it can happen very early in life, even before birth. In other instances it’s delayed until maturity, perhaps because the incipient mutations are suppressed by the immune system, until the time when ageing sets in and the system begins to weaken.”
I had to wait a little while for her next question, though I knew what it would be.
“Where do the dreams fit in?” she asked.
“They don’t,” I told her. “Not into the biology. I never really thought they did. They’re a psychological thing. There’s no psychotropic protein involved here. What we’re talking about is a slight failure of the switching mechanism that determines physical structure. Ann, the nightmares come from the same place as the Esoteric Order of Dagon and Zadok Allen’s fantasies—they’re a response to fear, anxiety and shame. They’re infectious in exactly the same way that rumors are infectious—people hear them, and reproduce
