Manual of Equine Anesthesia and Analgesia. Группа авторов
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F Priapism (see Chapter 38)
Phenylephrine can be used to treat priapism.
Phenylephrine HCl: 5–10 mg diluted in 10 ml of physiologic saline solution injected into the corpus cavernosum penis usually results in rapid resolution of the condition.
G Reversal of neuromuscular block (see Chapter 15)
As previously mentioned, neostigmine and edrophonium are used to reverse non‐depolarizing neuromuscular blockade. They should be administered slowly IV, and an anticholinergic drug (e.g. atropine) is usually administered concurrently to prevent adverse muscarinic effects, particularly bradycardia.
When used to treat ileus, neostigmine is administered subcutaneously or by a slow IV infusion, thus bradycardia is less likely to occur.
H Spasmolytic effect
Scopolamine, also known as hyoscine‐N‐butylbromide, is a competitive antagonist of ACh at muscarinic receptors. It is used clinically in association with the NSAID dipyrone to treat horses with spasmodic colic, and to relax the rectum for a per‐rectum examination of the abdomen, primarily in horses with colic. It has also been used to treat anesthetized horses with bradycardia.
Suggested Reading
1 Abraham, G. (2016). The importance of muscarinic receptors in domestic animal diseases and therapy: current and future perspectives. Vet. J. 208: 13–21.
2 Schauvliege, S. and Gasthuys, F. (2013). Drugs for cardiovascular support in anesthetized horses. Vet. Clin. North Am. Equine Pract. 29: 19–49.
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