Essentials of Nuclear Medicine Physics, Instrumentation, and Radiation Biology. Rachel A. Powsner

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Essentials of Nuclear Medicine Physics, Instrumentation, and Radiation Biology - Rachel A. Powsner

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target="_blank" rel="nofollow" href="#ulink_64e93c41-b428-5f4b-a220-5ccd70e95933">Table 2.2 lists half and tenth value layer of lead for photons emitted by some common medical radionuclides.

      For a monoenergetic beam of photons, the linear attenuation coefficient, μ, is related to the HVL as follows:

mu equals 0.693 slash upper H upper V upper L

      Beam hardening

      When a beam contains photons of different energies such as an X‐ray beam, it is termed polychromatic. As a polychromatic beam penetrates a material, lower energy photons are extinguished or scattered preferentially over higher energy photons and the result is that, while the overall intensity is diminished, the average energy of the transmitted fraction of the beam is increased. This phenomenon is known as beam hardening. A hardened beam is more penetrating and so a second HVL or TVL will be slightly thicker than the first.

Schematic illustration of the amount of attenuation of a photon beam is dependent on the photon energy and the thickness (and/or atomic number) of the attenuator.

Nuclide Gamma energy (keV) Half‐value layer (cm) Tenth‐value layer (cm)
99mTc 140 0.03 0.09
67Ga 93, 185, 300, 393 0.07 0.41
123I 159 0.04 0.12
131I 364 0.3 1
18F 511 0.39 1.3
111In 172, 245 0.023 0.2
Schematic illustration of penetrating radiation and nonpenetrating radiation.

      Because of the strong electrical force between a charged particle and the atoms of an absorber, charged particles can be stopped by matter with relative ease. Compared to photons, they transfer a greater amount of energy in a shorter distance and come to rest more rapidly. For this reason, they are referred to as nonpenetrating radiation (see depiction of alpha and beta particles in Figure 2.7). In contrast to a photon of 100 keV which has a HVL of 4 cm in soft tissue, an electron of this energy would penetrate less than 0.00014 cm in soft tissue [1].

      Excitation

      Ionization

       Specific ionization

Schematic illustration of excitation and de-excitation. Schematic illustration of ionization.

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