Table of Contents
1 Cover
4 Preface
6 1 Introduction 1.1 Discovery and Nature of Enzyme 1.2 Enzyme Structure and Catalytic Function 1.3 Cofactors and Coenzymes 1.4 Molecular Recognition and Enzyme Specificity 1.5 Enzyme Classes and Nomenclature 1.6 Enzyme and Green Chemistry 1.8 The Winner of Year 2009: A Solvent‐Free Biocatalytic Process for Cosmetic and Personal Care Ingredients References
7 2 Organic Synthesis with Oxidoreductases 2.1 Oxidation Reactions 2.2 Reduction Reactions References
8 3 Organic Synthesis with Transferases 3.1 Transamination with Aminotransferases 3.2 Glycosyl‐transfer with glycosyltransferase 3.3 Phosphorylation with Kinases 3.4 Acetyl Group Transfer with Acetyltransferase References
9 4 Organic Synthesis with Hydrolases 4.1 Hydrolysis of Ester Bond 4.2 Hydrolysis of Amide Bond 4.3 Hydrolysis of Phosphate Esters 4.4 Hydrolysis of Epoxides 4.5 Hydrolysis of Hydantoins 4.6 Hydrolysis of Glycosidic Bonds and Natural Polysaccharide References
10 5 Organic Synthesis with Lyases 5.1 Lyases with Carbon–Carbon Bonds 5.2 Lyases with Carbon–Oxygen Bonds 5.3 Lyases with Carbon–Nitrogen Bonds 5.4 Lyases with Carbon–Sulfur Bonds 5.5 Lyases with Carbon–Halide Bonds References
11 6 Organic Synthesis with Isomerases 6.1 Racemases and Epimerases 6.2 Cis‐Trans Isomerase 6.3 Intramolecular Oxidoreductases 6.4 Intramolecular Transferases 6.5 Intramolecular Lyases References
12 7 Organic Synthesis with Ligases 7.1 Ligases for Carbon–Oxygen Bonds Formation 7.2 Ligases for Carbon–Sulfur Bonds Formation 7.3 Ligases for Carbon–Nitrogen Bonds Formation 7.4 Ligases for Carbon–Carbon Bonds Formation References
13 8 Future Perspectives 8.1 Combinatorial Enzymatic Organic Synthesis 8.2 Artificial Intelligence Assisted Enzymatic Organic Synthesis References
14 Index
List of Tables
1 Chapter 1Table 1.1 Turnover numbers for some enzymes.Table 1.2 Some inorganic metal ions as cofactor of enzymes.Table 1.3 Some coenzymes as transient carriers of specific atoms or functio...Table 1.4 Six major classes of enzyme.Table 1.5 Twelve principles of green chemistry.
List of Illustrations
1 Chapter 1Scheme 1.1 The primary structure of a polypeptide chain linked by the peptid...Scheme
