Взломавшая код. Дженнифер Даудна, редактирование генома и будущее человечества. Уолтер Айзексон

Чтение книги онлайн.

Читать онлайн книгу Взломавшая код. Дженнифер Даудна, редактирование генома и будущее человечества - Уолтер Айзексон страница 22

Взломавшая код. Дженнифер Даудна, редактирование генома и будущее человечества - Уолтер Айзексон

Скачать книгу

style="font-size:15px;">      Jack Szostak. “Enzymatic Activity of the Conserved Core of a Group I Self-Splicing Intron” // Nature, 3 июля 1986 г.

      42

      Интервью автора с Ричардом Лифтоном, Дженнифер Даудной и Джеком Шостаком; вручение Дженнифер Даудне премии Грингарда 2 октября 2018 г.; Jennifer Doudna and Jack Szostak. “RNA-Catalysed Synthesis of Complementary-Strand RNA” // Nature, 15 июня 1989 г.; J. Doudna, S. Couture, and J. Szostak. “A Multisubunit Ribozyme That Is a Catalyst of and Template for Complementary Strand RNA Synthesis” // Science, 29 марта 1991 г.; J. Doudna, N. Usman, and J. Szostak. “Ribozyme-Catalyzed Primer Extension by Trinucleotides” // Biochemistry, 2 марта 1993 г.

      43

      Jayaraj Rajagopal, Jennifer Doudna, and Jack Szostak. “Stereochemical Course of Catalysis by the Tetrahymena Ribozyme” // Science, 12 мая 1989 г.; Doudna and Szostak. “RNA-Catalysed Synthesis of Complementary-Strand RNA”; J. Doudna, B. P. Cormack, and J. Szostak. “RNA Structure, Not Sequence, Determines the 5’ Splice-Site Specificity of a Group I Intron” // PNAS, октябрь 1989 г.; J. Doudna and J. Szostak. “Miniribozymes, Small Derivatives of the sunY Intron, Are Catalytically Active” // Molecular and Cell Biology, декабрь 1989 г.

      44

      Интервью автора с Джеком Шостаком.

      45

      Интервью автора с Джеймсом Уотсоном; James Watson et al. “Evolution of Catalytic Function”. Cold Spring Harbor Symposium, vol. 52, 1987.

      46

      Интервью автора с Дженнифер Даудной и Джеймсом Уотсоном; Jennifer Doudna… Jack Szostak, et al. “Genetic Dissection of an RNA Enzyme”. Cold Spring Harbor Symposium, 1987, p. 173.

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

Скачать книгу