A.M. and Wasterlain, C.G. (1999) N-methyl-D-asparate receptor antagonists abolish the maintenance phase of self-sustaining status epilepticus in rat. Neuroscience Letters 265, 187–190.
McNamara, J.O. (1999) Emerging insights into the genesis of epilepsy. Nature 399, A15–22.
Meisler, M.H., Kearney, J., Ottman, R. and Escayg, A. (2001) Identification of epilepsy genes in human and mouse. Annual Review of Genetics 35, 567–588.
Meldrum, B.S. (1994) The role of glutamate in epilepsy and other CNS disorders. Neurology 44, S14–23.
Meldrum, B.S. and Chapman, A.G. (1999) Excitatory amino acid receptors and antiepileptic drug development. Advances in Neurology 79, 965–978.
Meldrum, B.S., Akbar, M.T. and Chapman, A.G. (1999) Glutamate receptors and transporters in genetic and acquired models of epilepsy. Epilepsy Research 36, 189–204.
Mikati, M.A., Saab, R., Fayad, M.N. and Choueiri, R.N. (2002) Efficacy of intravenous immunoglobulin in Landau-Kleffner syndrome. Pediatric Neurology 26, 298–300.
Mikati, M.A., Kurdi, R., El-Khoury, Z., Rahi, A. and Raad, W. (2010) Intravenous immunoglobulin therapy in intractable childhood epilepsy: open-label study and review of the literature. Epilepsy and Behavior 17, 90–94.
Miles, R. and Wong, R.K. (1983) Single neurones can initiate synchronized population discharge in the hippocampus. Nature 306, 371–373.
Moldrich, R.X., Chapman, A.G., De Sarro, G. and Meldrum, B.S. (2003) Glutamate metabotropic receptors as targets for drug therapy in epilepsy. European Journal of Pharmacology 476, 3–16.
Moody, W.J., Futamachi, K.J. and Prince, D.A. (1974) Extracellular potassium activity during epileptogenesis. Experimental Neurology 42, 248–263.
Mori, A., Hiramatsu, M., Namba, S., Nishimoto, A., Ohmoto, T., Mayanagi, Y. and Asakura, T. (1987) Decreased dopamine level in the epileptic focus. Research Communications in Chemical Pathology and Pharmacology 56, 157–164.
Morita, T., Takahashi, M., Takeuchi, T., Hikasa, Y., Ikeda, S., Sawada, M., Sato, K., Shibahara, T. and Shimada, A. (2005) Changes in extracellular neurotransmitters in the cerebrum of familial idiopathic epileptic shetland sheepdogs using an intracerebral microdialysis technique and immunohistochemical study for glutamate metabolism. Journal of Veterinary Medical Science 67, 1119–1126.
Nadler, J.V. (2003) The recurrent mossy fiber pathway of the epileptic brain. Neurochemical Research 28, 1649–1658.
Nguyen, M.D., Julien, J.P. and Rivest, S. (2002) Innate immunity: the missing link in neuroprotection and neurodegeneration? Nature Reviews Neuroscience 3, 216–227.
Olsen, R.W., Wamsley, J.K., Mccabe, R.T., Lee, R.J. and Lomax, P. (1985) Benzodiazepine/gamma-aminobutyric acid receptor deficit in the midbrain of the seizure-susceptible gerbil. Proceedings of the National Academy of Sciences USA 82, 6701–6705.
Patrylo, P.R., Van Den Pol, A.N., Spencer, D.D. and Williamson, A. (1999) NPY inhibits glutamatergic excitation in the epileptic human dentate gyrus. Journal of Neurophysiology 82, 478–483.
Perkins, N.D. (2007) Integrating cell-signalling pathways with NF-kappaB and IKK function. Nature Reviews – Molecular Cell Biology 8, 49–62.
Pilz, D.T., Matsumoto, N., Minnerath, S., Mills, P., Gleeson, J.G., Allen, K.M., Walsh, C.A., Barkovich, A.J., Dobyns, W.B., Ledbetter, D.H. and Ross, M.E. (1998) LIS1 and XLIS (DCX) mutations cause most classical lissencephaly, but different patterns of malformation. Human Molecular Genetics 7, 2029–2037.
Pinto, D.J., Patrick, S.L., Huang, W.C. and Connors, B.W. (2005) Initiation, propagation, and termination of epileptiform activity in rodent neocortex in vitro involve distinct mechanisms. Journal of Neuroscience 25, 8131–8140.
Pitkanen, A. and Lukasiuk, K. (2009) Molecular and cellular basis of epileptogenesis in symptomatic epilepsy. Epilepsy and Behavior 14 (Suppl 1), 16–25.
Pitkanen, A. and Sutula, T.P. (2002) Is epilepsy a progressive disorder? Prospects for new therapeutic approaches in temporal-lobe epilepsy. Lancet Neurology 1, 173–181.
Podell, M. and Hadjiconstantinou, M. (1997) Cerebrospinal fluid gamma-aminobutyric acid and glutamate values in dogs with epilepsy. American Journal of Veterinary Research 58, 451–456.
Podell, M. and Hadjiconstantinou, M. (1999) Low concentrations of cerebrospinal fluid GABA correlate to a reduced response to phenobarbital therapy in primary canine epilepsy. Journal of Veterinary Internal Medicine 13, 89–94.
Przewlocka, B., Lason, W., Machelska, H., Van Luijtelaar, G., Coenen, A. and Przewlocki, R. (1995) Kappa opioid receptor agonists suppress absence seizures in WAG/Rij rats. Neuroscience Letters 186, 131–134.
Rakic, P. (1988) Specification of cerebral cortical areas. Science 241, 170–176.
Ransohoff, R.M., Kivisakk, P. and Kidd, G. (2003) Three or more routes for leukocyte migration into the central nervous system. Nature Reviews - Immunology 3, 569–581.
Ravizza, T. and Vezzani, A. (2006) Status epilepticus induces time-dependent neuronal and astrocytic expression of interleukin-1 receptor type I in the rat limbic system. Neuroscience 137, 301–308.
Ravizza, T., Gagliardi, B., Noe, F., Boer, K., Aronica, E. and Vezzani, A. (2008) Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiology of Disease 29, 142–160.
Rice, A.C. and DeLorenzo, R.J. (1998) NMDA receptor activation during status epilepticus is required for the development of epilepsy. Brain Research 782, 240–247.
Richerson, G.B. (2004) Looking for GABA in all the wrong places: the relevance of extrasynaptic GABA(A) receptors to epilepsy. Epilepsy Currents 4, 239–242.
Rizzi, M., Perego, C., Aliprandi, M., Richichi, C., Ravizza, T., Colella, D., Veliskova, J., Moshe, S.L., De Simoni, M.G. and Vezzani, A. (2003) Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development. Neurobiology of Disease 14, 494–503.
Rogawski, M.A. and Donevan, S.D. (1999) AMPA receptors in epilepsy and as targets for antiepileptic drugs. Advances in Neurology 79, 947–963.
Rothwell, N.J. (1989) CRF is involved in the pyrogenic and thermogenic effects of interleukin 1 beta in the rat. American Journal of Physiology 256, E111–115.
Rutecki, P.A., Lebeda, F.J. and Johnston, D. (1985) Epileptiform activity induced by changes in extracellular potassium in hippocampus. Journal of Neurophysiology 54, 1363–1374.
Rutecki, P.A., Grossman, R.G., Armstrong, D. and Irish-Loewen, S. (1989) Electrophysiological connections between the hippocampus and entorhinal cortex in patients with complex partial seizures. Journal of Neurosurgery 70, 667–675.
Saito, M., Sharp, N.J., Kortz, G.D., De Lahunta, A., Leventer, R.J., Tokuriki, M. and Thrall, D.E. (2002) Magnetic resonance imaging features of lissencephaly in 2 Lhasa Apsos. Veterinary Radiology and Ultrasound 43, 331–337.
