Brandt, C., Glien, M., Gastens, A.M., Fedrowitz, M., Bethmann, K., Volk, H.A., Potschka, H. and Löscher, W. (2007) Prophylactic treatment with levetiracetam after status epilepticus: lack of effect on epileptogenesis, neuronal damage, and behavioral alterations in rats. Neuropharmacology 53, 207–221.
Brini, E., Gandini, G., Crescio, I., Fatzer, R. and Casalone, C. (2004) Necrosis of hippocampus and piriform lobe: clinical and neuropathological findings in two Italian cats. Journal of Feline Medicine and Surgery 6, 377–381.
Casal, M.L., Munuve, R.M., Janis, M.A., Werner, P. and Henthorn, P.S. (2006) Epilepsy in Irish Wolfhounds. Journal of Veterinary Internal Medicine 20, 131–135.
Chandler, K. (2006) Canine epilepsy: what can we learn from human seizure disorders? The Veterinary Journal 172, 207–217.
Chang, Y., Mellor, D.J. and Anderson, T.J. (2006) Idiopathic epilepsy in dogs: owners’ perspectives on management with phenobarbitone and/or potassium bromide. Journal of Small Animal Practice 47, 574–581.
Cowan, L.D. (2002) The epidemiology of the epilepsies in children. Mental Retardation and Developmental Disabilities Research Reviews 8, 171–181.
Dalmau, J., Gleichman, A.J., Hughes, E.G., Rossi, J.E., Peng, X., Lai, M., Dessain, S.K., Rosenfeld, M.R., Balice-Gordon, R. and Lynch, D.R. (2008) Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurology 7, 1091–1098.
Dewey, C.W., Guiliano, R., Boothe, D.M., Berg, J.M., Kortz, G.D., Joseph, R.J. and Budsberg, S.C. (2004) Zonisamide therapy for refractory idiopathic epilepsy in dogs. Journal of the American Animal Hospital Association 40, 285–291.
Dewey, C.W., Cerda-Gonzalez, S., Levine, J.M., Badgley, B.L., Ducoté, J.M., Silver, G.M., Cooper, J.J., Packer, R.A. and Lavely, J.A. (2009) Pregabalin as an adjunct to phenobarbital, potassium bromide, or a combination of phenobarbital and potassium bromide for treatment of dogs with suspected idiopathic epilepsy. Journal of the American Veterinary Medical Association 235, 1442–1449.
Elsharkawy, A.E., May, T., Thorbecke, R. and Ebner, A. (2009) Predictors of quality of life after resective extratemporal epilepsy surgery in adults in long-term follow-up. Seizure 18, 498–503.
Fatzer, R., Gandini, G., Jaggy, A., Doherr, M. and Vandevelde, M. (2000) Necrosis of hippocampus and piri-form lobe in 38 domestic cats with seizures: a retrospective study on clinical and pathologic findings. Journal of Veterinary Internal Medicine 14, 100–104.
Fluehmann, G., Doherr, M.G. and Jaggy, A. (2006) Canine neurological diseases in a referral hospital population between 1989 and 2000 in Switzerland. Journal of Small Animal Practice 47, 582–587.
Fromm, M.F. (2000) P-glycoprotein: a defense mechanism limiting oral bioavailability and CNS accumulation of drugs. International Journal of Clinical Pharmacology and Therapeutics 38, 69–74.
Gullov, C.H., Toft, N., Baadsager, M.M. and Berendt, M. (2011) Epilepsy in the Petit Basset Griffon Vendeen: prevalence, semiology, and clinical phenotype. Journal of Veterinary Internal Medicine 25, 1372–1378.
Heynold, Y., Faissler, D., Steffen, F. and Jaggy, A. (1997) Clinical, epidemiological and treatment results of idiopathic epilepsy in 54 labrador retrievers: a long-term study. Journal of Small Animal Practice 38, 7–14.
Hoffmann, K., Gastens, A.M., Volk, H.A. and Löscher, W. (2006) Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats. Epilepsy Research 69, 1–14.
Hülsmeyer, V., Zimmermann, R., Brauer, C., Sauter-Louis, C. and Fischer, A. (2010) Epilepsy in Border Collies: clinical manifestation, outcome, and mode of inheritance. Journal of Veterinary Internal Medicine 24, 171–178.
Jaggy, A., Faissler, D., Gaillard, C., Srenk, P. and Graber, H. (1998) Genetic aspects of idiopathic epilepsy in Labrador retrievers. Journal of Small Animal Practice 39, 275–280.
Johnson, M.R. and Shorvon, S.D. (2011) Heredity in epilepsy: neurodevelopment, comorbidity, and the neurological trait. Epilepsy and Behavior 22, 421–427.
Jokinen, T.S., Metsähonkala, L., Bergamasco, L., Viitmaa, R., Syrjä, P., Lohi, H., Snellman, M., Jeserevics, J. and Cizinauskas, S. (2007) Benign familial juvenile epilepsy in Lagotto Romagnolo dogs. Journal of Veterinary Internal Medicine 21, 464–471.
Kathmann, I., Jaggy, A., Busato, A., Bartschi, M. and Gaillard, C. (1999) Clinical and genetic investigations of idiopathic epilepsy in the Bernese mountain dog. Journal of Small Animal Practice 40, 319–325.
Kearsley-Fleet, L., ONeill, D.G., Volk, H.A., Church, D.B. and Brodbelt, D.C. (2013) Prevalence and risk factors for canine epilepsy of unknown origin in the UK. Veterinary Record 172(13), 338.
Kennerly, E.M., Idaghdour, Y., Olby, N.J., Muñana, K.R. and Gibson, G. (2009) Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs. Pharmacogenetics and Genomics 19, 911–922.
Kuwabara, T., Hasegawa, D., Kobayashi, M., Fujita, M. and Orima, H. (2010) Clinical magnetic resonance volumetry of the hippocampus in 58 epileptic dogs. Veterinary Radiology and Ultrasound 51, 485–490.
Kwan, P. and Brodie, M.J. (2000) Early identification of refractory epilepsy. The New England Journal of Medicine 342, 314–319.
Kwan, P., Sills, G.J., Butler, E., Gant, T.W., Meldrum, B.S. and Brodie, M.J. (2002) Regional expression of multidrug resistance genes in genetically epilepsy-prone rat brain after a single audiogenic seizure. Epilepsia 43, 1318–1323.
Kwan, P., Poon, W.S., Ng, H.K., Kang, D.E., Wong, V., Ng, P.W., Lui, C.H., Sin, N.C., Wong, K.S. and Baum, L. (2008) Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression. Pharmacogenetics and Genomics 18, 989–998.
Kwan, P., Arzimanoglou, A., Berg, A.T., Brodie, M.J., Allen Hauser, W., Mathern, G., Moshé, S.L., Perucca, E., Wiebe, S. and French, J. (2010) Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 51, 1069–1077.
Kwan, P., Schachter, S.C. and Brodie, M.J. (2011) Drug-resistant epilepsy. The New England Journal of Medicine 365, 919–926.
Lancaster, E., Lai, M., Peng, X., Hughes, E., Constantinescu, R., Raizer, J., Friedman, D., Skeen, M.B., Grisold, W., Kimura, A., Ohta, K., Iizuka, T., Guzman, M., Graus, F., Moss, S.J., Balice-Gordon, R. and Dalmau, J. (2010) Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. Lancet Neurology 9, 67–76.
Löscher, W. and Brandt, C. (2010) High seizure frequency prior to antiepileptic treatment is a predictor of pharmacoresistant epilepsy in a rat model of temporal lobe epilepsy. Epilepsia 51, 89–97.
Löscher, W. and Potschka, H. (2002) Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. The Journal of Pharmacology and Experimental Therapeutics 301, 7–14.
Löscher, W. and Potschka, H. (2005) Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases. Progress in Neurobiology
