Conclusion and Future Directions
References
23 15 Application of Metabolomics in Emergency Phytochemical Poisoning and Remediation 15.1 Introduction 15.2 Traditional Use of Medicinal Plants 15.3 Natural Products: Safety and Toxicity 15.4 Biological Systems in Phytochemical Poisoning and Remediation 15.5 Metabolomics: An Important Functional Genomics Tool 15.6 Assessment of Toxicity of Herbal Medicines Using Metabolomics 15.7 Application of Metabolomics in Emergency Phytochemical Poisoning and Remediation 15.8 Conclusion References
24 16 Methods for the Detection and Identification of Phytotoxins 16.1 Introduction 16.2 Phytotoxins 16.3 Methods Generally Used for Phytotoxin Detection 16.4 Protease Inhibition Detection Protocol 16.5 Isolation of Phytotoxins from Microorganisms 16.6 Conclusion References
25 17 Categorization, Management, and Regulation of Potentially Weaponizable Toxic Plants 17.1 Introduction 17.2 Management of Weaponized Natural Food Agents 17.3 Techniques Used for Extraction, Segregation, and Decontamination of Phytochemicals 17.4 Techniques for Identification of Bioactive Compounds 17.5 Types of Natural Phytotoxins 17.6 Conclusion References
26 18 In Silico Modeling as a Tool to Predict and Characterize Plant Toxicity 18.1 Introduction 18.2 Components of In Silico Toxicity Methods 18.3 Modeling Methods 18.4 Structural Alerts/Rule Based 18.5 Statistical Structure‐Based Activity Relationship Models 18.6 Conclusion References
27 Index
List of Tables
1 Chapter 1Table 1.1 Some common drugs derived from toxic plants.
2 Chapter 3Table 3.1 Selected poisonous plants from around the world.Table 3.2 Drugs from poisonous plants used as anticancer agents.Table 3.3 Some examples of drugs developed from poisonous plants.
3 Chapter 7Table 7.1 Some other classes of phytochemicals possessing sedative–hypnotic a...Table 7.2 Plants with reported sedative actions.
4 Chapter 8Table 8.1 Bioactive compounds of edible mushroom species.Table 8.2 Bioactive compounds of non‐edible mushroom species.
5 Chapter 9Table 9.1 Globally Harmonized System of Classification and Labelling of Chemi...Table 9.2 Draize irritation potential classification [51, 54].
6 Chapter 12Table 12.1 Effects of heavy metals on the human body.
7 Chapter 13Table 13.1 Medicinal plants that inhibit snake venom effects.
8 Chapter 14Table 14.1 Phytochemicals used in the synthesis of nanoparticles.
9 Chapter 15Table 15.1 Some selected examples of well‐known herbal remedies traditionally...
10 Chapter 16Table 16.1 Common phytotoxins present in plant families.Table 16.2 Classic examples of methods used to detect phytotoxins.
11 Chapter 18Table 18.1 Workflow involved when designing in silico toxicity prediction mod...
List of Illustrations
1 Chapter 6Figure 6.1 Penetration of sulfur mustard (HD) into skin through hair follicl...Figure 6.2 Skin exposure to sulfur mustard (HD).Figure 6.3 Adverse effects of sulfur mustard (HD) on various organs.Figure 6.4 The activation process of sulfur mustard (HD).Figure 6.5 A simple process illustrating nicotinamide adenine dinucleotide (...Figure 6.6 Sulfur mustard (HD) blister formation as a result of increased le...
2 Chapter 7Figure 7.1 Chemical structures of flavonoids reported to have sedative–hypno...Figure 7.2 Chemical structures of some sedative–hypnotic alkaloids.Figure 7.3 Chemical structures of some sedative–hypnotic volatile constituen...Figure 7.4 Chemical structures of some natural bioactive phytosedatives.
3 Chapter 11Figure 11.1 Structures of some antimicrobial agents obtained from microbes....Figure 11.2 Antifungal agents from microbial sources.Figure 11.3 Anticancer agents from microbial sources.Figure 11.4 Hypocholesterolemic agents from microbial sources.Figure 11.5 Immunosuppressants from microbial sources.Figure 11.6 Enzyme inhibitors from microbial sources.
4 Chapter 12Figure 12.1 The structure of galacturonic acid.Figure 12.2 Myoinositol hexaphosphoric acid (phytic acid).Figure 12.3 Phytochelatin.Figure 12.4 Ellagic acid.
5 Chapter 13Figure 13.1 Mechanism of nanoformulation in targeted and controlled delivery...Figure 13.2 Schematic representation of the probable mechanism of action of ...
6 Chapter
