Principles of Virology. Jane Flint

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are produced to explain this UV sensitivity map.

      7 Influenza virus mRNAs are shorter than the genomic RNAs from which they are made. What is the mechanism for production of full-length copies of the genomic (–) strand RNAs for incorporation into newly synthesized virus particles?

      8 Some RdRPs require a primer to initiate RNA synthesis. What are two different types of primer used for RNA synthesis?

      9 The palm domain of poliovirus RdRP contains a GDD motif. Explain why changing D (Asp) to alanine produces an inactive polymerase that can no longer copy RNA templates.

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