The Drug Recognition Guide. Mark Currivan
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Lansoprazole
Omeprazole
Pantoprazole
Rabeprazole
Note an exception: a drug ending in ‘‐prazole’ that is not a proton pump inhibitor: aripiprazole (an atypical antipsychotic drug: see Chapter 5).
Do not mistake PPIs ending in ‘‐prazole’ for antibiotics ending in ‘‐nidazole’ (i.e., metronidazole) or ‘‐oxazole’ (i.e., co‐trimoxazole) (see Chapter 9); or antifungals ending in ‘‐conazole’ (i.e., fluconazole: Chapter 9) or hormone antagonists ending in ‘‐rozole’ (i.e., letrozole: Chapter 10) [chemically, all of the above are azole derivatives, hence their ‘‐zole’ suffix].
References
1 Ford, A.C., Talley, N.J., Spiegel, B.M. et al. (2008). Effect of fibre, antispasmodics and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta‐analysis. British Medical Journal, 337, a2313.
2 Keshav, S. and Bailey, A. (2013). The gastrointestinal system at a glance. 2nd ed. Chichester: Wiley Blackwell.
3 Puttmann, M. and Roett, M.A. (2011). H2 blockers are as effective as PPIs for long‐term relief of non‐ulcer dyspepsia. Evidence‐Based Practice, 14 (2), 14.
4 Ruepert, L., Quartero, A.O., de Wit, N.J. et al. (2011). Bulking agents, antispasmodics and antidepressants for the treatment of irritable bowel syndrome. Cochrane Database of Systematic Reviews [online]. Available from: doi: 10.1002/14651858.CD003460.pub3.
5 Savarino, V., Dulbecco, P., de Bortoli, N. et al. (2017). Appropriate use of proton pump inhibitors (PPIs): need for a reappraisal. European Journal of Internal Medicine, 37, 19–24 [online]. Available from: doi: 10.1016/j.ejim.2016.10.007.
6 Strand, D.S., Kim, D. and Peura, D.A. (2017). 25 years of proton pump inhibitors: a comprehensive review. Gut and Liver, 11 (1), 27–37 [online]. Available from: doi: 10.5009/gnl.15502.
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