Acute Kidney Injury - Basic Research and Clinical Practice. Группа авторов

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Acute Kidney Injury - Basic Research and Clinical Practice - Группа авторов Contributions to Nephrology

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is located. This assessment is ideally situated in the electronic medical record and accessible by all team members. The proposed algorithm is based on the 4 simple steps named the “Fantastic 4” that evaluates the patient systematically and promptly referring them to nephrologists to improve outcome (Fig. 3).

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      The approach to the patient should be the following:

      F1: refer the patient to a “clinical scenario” where the patient’s signs and symptoms and the surrounding circumstances and risks are reviewed and considered;

      F2: interview the patient or his/her relatives and review the “past history” with a goal of identifying the level of susceptibility and intensity of exposures;

      F3: conduct a “physical examination” on the patient aiming at characterizing hemodynamic instability, volume depletion or fluid overload and signs/source of infection, if any;

      F4: analyze “laboratory results” including possible AKI biomarkers to complete the patient risk stratification.

      This AKI F4 model is considered collaborated with the electronic medical record to alert caregivers to the risk assessment results.

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      Conclusions

      AKI has been identified as a commonly occurring independent risk factor for causing morbidity and mortality. Given that there are no effective therapies to treat AKI, prevention is critical to improve outcomes. The quality of assessing AKI risk shall be improved for effective prevention. The methodology of quality measure shall be scientific and reasonable.

      References

      3Kaufman J, Dhakal M, Patel B, Hamburger R: Community-acquired acute renal failure. Am J Kidney Dis 1991;17:191–198.

      15Hsu CY, Chertow GM, McCulloch CE, Fan D, Ordonez JD, Go AS: Nonrecovery of kidney function and death after acute on chronic renal failure. Clin J Am Soc Nephrol 2009;4:891–898.

      16Hsu CY, Ordonez JD, Chertow GM, Fan D, McCulloch CE, Go AS: The risk of acute renal failure in patients with chronic kidney disease. Kidney Int 2008;74:101–107.

      17Khosla N, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini E, Mehta RL: Preexisting chronic kidney disease: a potential for improved outcomes from acute kidney injury. Clin J Am Soc Nephrol 2009;4:1914–1919.

      18Lo LJ, Go AS, Chertow GM, McCulloch CE, Fan D, Ordonez JD, Hsu CY: Dialysis-requiring

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