is sent is as important as taking appropriate samples. Whenever possible, biopsies should be sent to a veterinary dermatopathologist. If a facility has multiple pathologists on staff, be sure to request the dermatopathologist for skin biopsies. A short history of the case including progression, response to therapy, and current therapies should be included. A description of the lesions that were biopsied, where they were obtained, and a differential diagnosis list should also be included. If possible, include several photographs of the lesions. This information will help the pathologist narrow their differential list and may assist them with keying in on specific structures. The report from the pathologist should include a complete microscopic description of the lesions and a comment on what disease the histopathologic changes best fit, plus other possibilities if the histopathology is not pathognomonic for a specific condition. There should also be recommendations from the pathologist on special stains and immunohistochemistry if indicated.
Remember that biopsies are just a diagnostic tool. The more complete information supplied to the pathologist about the patient and the clinical picture, the better the information the pathologist will be able to provide in return. If the results do not fit with the clinical picture or response to therapy, another biopsy should be taken.
Recommended Reading
1 Gross, T., Ihrke, P., Walder, E., and Affolter, V. (2005). Skin Diseases of the Dog and Cat: Clinical and Histopathologic Diagnosis, 2e. Ames, IA: Blackwell Science.
2 Yager, J. and Wilcock, B. (1994). Color Atlas and Text of Surgical Pathology of the Dog and Cat, Dermatopathology and Skin Tumors, vol. 1. St. Louis, MO: Mosby.
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