Diagnostics and Therapy in Veterinary Dermatology. Группа авторов

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Center Hereditary nasal parakeratosis, multidrug resistance (MDR1) Cheek swab Test results will determine if the animal is a carrier for the known mutation causing the disorder http://dnacenter.com/testing‐pets‐vets Embark (partnership with Cornell University College of Veterinary Medicine) Multidisease screening. Dystrophic epidermolysis bullosa, ectodermal dysplasia (skin fragility syndrome), ichthyosis, epidermolytic hyperkeratotic ichythyosis, focal non‐epidermolytic ichthyosis, palmoplantar keratoderma, pachyonychia congenita, hereditary footpad hyperkeratosis, hereditary nasal parakeratosis, Musladin‐Lueke syndrome, and bald thigh syndrome. Additional unlisted genetic tests are available by contacting the laboratory Cheek swab Whole‐genomic sequencing with microarray SNP chip technology. Test results will determine if the animal is a carrier for the known mutation causing the disorder http://embarkvet.com IDEXX Hereditary equine regional dermal asthenia (HERDA) in US laboratory; junctional epidermolysis bullosa (JEB1 and JEB2), hereditary nasal parakeratosis, dry eye curly coat syndrome, ichthyosis, and Musladin‐Lueke syndrome (beagle) in European laboratory Whole blood (EDTA) or cheek swab PCR test results will determine if the animal is a carrier for the known mutation causing the disorder www.idexx.com Institute of Genetics, University of Bern, Switzerland Genomic sequencing and DNA analysis Many sample types permitted. Contact laboratory regarding specific sample depending on test Research laboratory specializing in discovery and characterization of genetic diseases in animals, with an interest in dermatologic disorders https://www.genetics.unibe.ch/about_us/person/prof_dr_leeb_tosso/index_eng.html My Dog DNA Multidisease screening Cheek swab Test results will determine if the animal is a carrier for the known mutation causing the disorder www.mydogdna.com Optimal Selection™ Multidisease screening Cheek swab Test results will determine if the animal is a carrier for the known mutation causing the disorder www.optimal‐selection.com Orivet Genetic Pet Care Congenital hypothyroidism, dermatomyositis, dry eye curly coat syndrome, ectodermal dysplasia, dystrophic epidermolysis bullosa, hereditary footpad hyperkeratosis, hereditary nasal parakeratosis, ichthyosis, (golden retriever, American bulldog, Norfolk terrier, great Dane, German shepherd), lethal acrodermatitis, multidrug resistance (MDR1), Musladin‐Lueke syndrome, renal cystadenocarcinoma and nodular dermatofibrosis Cheek swab Test results will determine if the animal is a carrier for the known mutation causing the disorder www.orivet.com Paw Print Genetics of Genetic Veterinary Sciences and Canine Health Check (multidisease screening) Anhidrotic ectodermal dysplasia, ectodermal dysplasia, epidermolytic hyperkeratosis, ichythyosis, dystrophic epidermolysis bullosa, Musladin‐Lueke syndrome, dry eye curly coat syndrome, D locus (dilute), leukocyte adhesion deficiency type I, severe combined immunodeficiency disease (terrier type), renal cystadenocarcinoma and nodular dermatofibrosis, Glanzmann's thrombasthenia Many sample types are acceptable, including whole blood in EDTA and cheek swabs. Contact laboratory regarding specific sample depending on test Test results will determine if the animal is a carrier for the known mutation causing the disorder www.pawprintgenetics.com www.caninehealthcheck.com PennGen, University of Pennsylvania Congenital hypothyroidism, ectodermal dysplasia (skin fragility syndrome – Chesapeake Bay retriever), epidermolysis bullosa (Eurasier), ichthyosis (American bulldog), lethal acrodermatosis (bull terrier), leukocyte adhesion deficiency (type I), exfoliative cutaneous lupus erythematosus (German shorthaired pointer) Cheek swab or whole blood (EDTA) PCR test results will determine if the animal is a carrier for the known mutation causing the disorder. Comprehensive list of genetic tests available worldwide at the PennGen website http://www.vet.upenn.edu/research/academic‐departments/clinical‐sciences‐advanced‐medicine/research‐labs‐centers/penngen UC Davis Veterinary Genetics Laboratory Hereditary nasal parakeratosis Many sample types are acceptable, including cheek swab, whole blood in EDTA, and hair samples. Contact laboratory regarding specific sample depending on test Test results will determine if the animal is a carrier for the known mutation causing the disorder http://vgl.ucdavis.edu vetGen™ Veterinary Genetic Services Albinism in Doberman pinscher, canine cyclic neutropenia, dry eye curly coat, hereditary footpad hyperkeratosis, heredity nasal parakeratosis, Musladin‐Lueke syndrome, renal cystadenocarcinoma nodular dermatofibrosis Cheek swab Test results will determine if the animal is a carrier for the known mutation causing the disorder www.vetgen.com Wisdom Health, Wisdom Panel™, formerly Optigen Dermatomyositis, hereditary nasal parakeratosis, ichthyosis (golden retriever), multidisease screening Many sample types are acceptable, including cheek swab, whole blood in EDTA, semen, and tissue. Contact laboratory regarding specific sample depending on test Test results will determine if the animal is a carrier for the known mutation causing the disorder http://breeder.wisdompanel.com

There are three basic types of ELISA techniques: direct, indirect, and capture (sandwich) techniques (Tizard 2013). The direct method (

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