Pathy's Principles and Practice of Geriatric Medicine. Группа авторов

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≥65 3.7 Standardized for DRG 5.7±0.6 2.6±0.2 (16–44 yrs) p < 0.0001 Australia (Wilson) 1995 14,210 3945 (27.76%) ≥65 16.6 23.3 Mean 13.75 Not given Utah and Colorado (Thomas) 2000 15,000 Not stated ≥65 2.9±0.2 All adverse events 5.29±0.37 All adverse events 2.80±0.18 p = 0.001 UK (Vincent) 2001 1014 342 (33.73%) ≥65 10.8 18.13 (62/342) 7.25 (48/662) p < 0.001 New Zealand (Davis) 2002 6579 1967 (29.9%) ≥65 11.2 17.6 (346/1967) 10.93 (504/4612) Not given Canada (Ross‐Baker) 2004 3745 Not stated Not stated 7.5 Mean age of patient with adverse events 64.9 (SD 16.7) vs. 62.0 (SD 18.4) yrs, p = 0.016 Ottawa (Forster) 2004 502 126 (25.1%) >72 12.7 22.22 (28/126) 9.57 (36/376) p < 0.001 France (Michel) 2007 8754 Not stated Not stated 6.6 per 1000 days of hospitalization Mean age of those experiencing adverse events = 63 yrs, 61.7 yrs for those who did not (p = 0.5) UK (Sari) 2007 1006 332 (33.0%) ≥75 8.7 13.5 (95% CI 9.8–17.2) 6.2 (95% CI 4.4–8.0) p < 0.001 Portugal (Sousa) 2014 1669 Not stated >65 11.1 19.3 (59% of adverse events in >65 years) 8.2 Not stated Ireland (Rafter) 2016 1574 Not stated Not stated 10.3 Mean age of those experiencing adverse events = 61.8, vs. 55.4 P < 0.001 Sweden (Nilsson) 2018 64971 Not stated >65 11.7 12.9 9.6 P < 0.001

      Source: Adapted from Thomas and Petersen19.

Study method Advantages Disadvantages
Administrative data analysis Uses readily available data May rely on incomplete and inaccurate data
Inexpensive The data are divorced from clinical context
Record review/chart review Uses readily available data Judgements about adverse events not reliable
Commonly used Medical records are incomplete Hindsight bias
Review of electronic medical records Inexpensive after initial investment Monitors in real time Integrates multiple data sources Susceptible to programming and/or data‐entry errors Expensive to implement
Observation of patient care Potentially accurate and precise Provides data otherwise unavailable Detects more active errors than other methods Time‐consuming and expensive Difficult to train reliable observers Potential concerns about confidentiality Possible to be overwhelmed with information
Active clinical surveillance Potentially accurate and precise for adverse events Time‐consuming and expensive

      Source: Adapted from Thomas and Petersen19.

Study method Advantages Disadvantages
Morbidity and mortality conferences and autopsy Can suggest contributory factors Familiar to healthcare providers Hindsight bias Reporting bias Focused on diagnostic errors Infrequently used
Case analysis/root cause analysis Can suggest contributory structured systems approach Includes recent data from interviews

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