by simple binary fission, but those of Enterocytozoon have a more complex development which produces multinucleate cells. After several cycles of merogony, the parasites start to produce spores by sporogony: the meront transforms into a sporont which produce sporoblasts that then mature into spores. The spores steadily accumulate in the host cell and may eventually fill it. When the host cell membrane eventually ruptures, the spores are released and may infect an adjacent cell or be released into the environment.
In humans, microsporidia usually cause persistent or self‐limiting infections of the enterocytes lining the gastrointestinal tract. They can cause extensive damage to the mucosal surface of the intestine and symptoms therefore typically cause diarrhoea, abdominal pain, malabsorption and wasting. There are also records of them invading the eye and causing keratitis in both immunocompromised and immunocompetent individuals, as well as infecting the skin, kidney, heart, and lungs.
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