Bioinformatics. Группа авторов
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18 13 Biological Networks and Pathways Introduction Pathway and Molecular Interaction Mapping: Experiments and Predictions Pathway and Molecular Interaction Databases: An Overview Pathway Databases Molecular Interaction Databases Functional Interaction Databases Strategies for Navigating Pathway and Interaction Databases Standard Data Formats for Pathways and Molecular Interactions Pathway Visualization and Analysis Network Visualization and Analysis Summary Acknowledgments Internet Resources Further Reading References
19 14 Metabolomics Introduction Data Formats Databases Bioinformatics for Metabolite Identification Multivariate Statistics Bioinformatics for Metabolite Interpretation Summary Further Reading References
20 15 Population Genetics Introduction Evolutionary Processes and Genetic Variation Allele Frequencies and Population Variation Display Methods Demographic History Inference Admixture and Ancestry Estimation Detection of Natural Selection Other Applications Summary References
21 16 Metagenomics and Microbial Community Analysis Introduction Why Study the Microbiome? The Origins of Microbiome Analysis Metagenomic Workflow General Considerations in Marker-Gene and Metagenomic Data Analysis Marker Genes Metagenomic Data Analysis Other Techniques to Characterize the Microbiome Summary Further Reading References
22 17 Translational Bioinformatics Introduction Databases Describing the Genetics of Human Health Prediction and Characterization of Impactful Genetic Variants from Sequence Computing with Patient Phenotype Using Data in Electronic Health Records Informatics and Precision Medicine Ethical, Legal, and Social Implications of Translational Medicine Summary References
23 18 Statistical Methods for Biologists Introduction Descriptive Representations of Data Statistical Inference and Statistical Hypothesis Testing Summary Acknowledgments Internet Resources Further Reading References
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Appendices
1.1 Example of a Flatfile Header in ENA Format
1.2 Example of a Flatfile Header in DDBJ/GenBank Format
1.3 Example of a Feature Table in ENA Format
1.4 Example of a Feature Table in GenBank/DDBJ Format
6.1 Dynamic Programming