Introduction
Royal Pharmaceutical Society
The Nursing and Midwifery Council
Pharmacokinetics
Pharmacokinetic principles (the ADME process)
Phase 1: Absorption
Phase 2: Distribution
Phase 3: Metabolism (Biotransformation)
Phase 4: Elimination
An example of the pharmacokinetics of aspirin
Routes of drug administration
Pharmacodynamics
Agonists and antagonists
Drug potency and efficacy
Therapeutic index
Adverse effects
Conclusion
References
Multiple choice questions
14 Chapter 6: Drug formulations Aim Introduction Tablets Buccal/sublingual Oral Topical Rectal Vaginal Inhalation Injection routes Conclusion References Further reading Multiple choice questions
15 Chapter 7: Adverse drug reaction Definition – what is an adverse drug reaction The prevalence of adverse reactions The ABCDE classification of adverse reactions The signs and symptoms of adverse effects Physical signs of an adverse drug reaction may include the following Adverse reaction diagnosis and management Reporting incidents of adverse drug reactions Conclusion References Further reading Multiple choice questions
16 Chapter 8: Analgesics Aim Introduction Pain pathways Definitions and categories of pain Importance of individualised pain assessments Assessment tools Multimodal management strategies Pharmacological management Non‐opioids Non‐steroidal anti‐inflammatories (NSAIDs) Opioid agonists Codeine phosphate Dihydrocodeine Tramadol Morphine Fentanyl Adjuvants and co‐analgesics – gabapentinoids Inhalation analgesics Local and regional anaesthesia Conclusion References Multiple choice questions Find out more
17 Chapter 9: Antibacterials Introduction Language and terminology Antibacterial mechanisms of action Choosing the right treatment Antimicrobial resistance Antibacterials by action Beta‐lactams Protein synthesis interference
