15.6 Examples of monoclonal antibodies.Table 15.7 Demonstrates properties of Rituximab as a monoclonal antibody.Table 15.8 Other checkpoint inhibitors.Table 15.9 Indications for use of transplant.Table 15.10 Examples of adoptive cell transfer drugs.Table 15.11 Examples of cytokines.Table 15.12 Side effects of immunotherapy.Table 15.13 Examples of corticosteroid use in cancer.Table 15.14 Examples of corticosteroid.Table 15.15 Dexamethasone.Table 15.16 Side effects of Corticosteroids.12 Chapter 16Table 16.1 Classification of seizuresTable 16.2 AED by seizure type
13 c17Table 17.1 Required washout periods when switching to an MAOITable 17.2 Symptoms associated with hyponatremiaTable 17.3 Risk factors for developing antidepressant related hyponatremiaTable 17.4 Symptoms of serotonin syndromeTable 17.5 Antidepressant discontinuation symptomsTable 17.6 Antipsychotic related side effectsTable 17.7 Antipsychotic pre‐treatment monitoringTable 17.8 Principles of sleep hygiene.
14 Chapter 18Table 18.1 Vaccine‐preventable diseases.Table 18.2 National immunisation programs.Table 18.3 Pharmacodynamics and pharmacokinetics of vaccines.
List of Illustrations
1 Chapter 1Figure 1.1 A systematic approach to care provision.Figure 1.2 The Code. Source: Olympus America, Inc. With permission.
2 Chapter 2Figure 2.1 Extract drug class monograph.Figure 2.2 Contraindication and class monograph.Figure 2.3 Home page of MIMS online.Figure 2.4 How to determine if a drug or devise can be prescribed on the NHS...
3 Chapter 3Figure 3.1 Acts or laws affecting the provision of medicines.
4 Chapter 5Figure 5.1 An integration of ADME and the routes of administration.Figure 5.2 Medication delivery to baby during gestation.Figure 5.3 Hepatic first‐pass metabolism (first‐pass effect).Figure 5.4 Pharmacokinetics (ADME) and the main anatomical structures/physio...Figure 5.5 Injectable routes of administration.Figure 5.6 Diagram illustrating how a transdermal patch works.Figure 5.7 (a) The step‐by‐step process of a second messenger system. (b) St...
5 Chapter 6Figure 6.1 Sublingual and buccal routes.
6 Chapter 7Figure 7.1 Anaphylaxis eyes.Figure 7.2 Anaphylaxis lips.Figure 7.3 Anaphylaxis tongue.Figure 7.4 Rash.Figure 7.5 Serum sickness.Figure 7.6 ‘Yellow Card’ notification for suspected adverse drug reactions....
7 Chapter 8Figure 8.1 Pain pathway.Figure 8.2 Types of pain.Figure 8.3 Example of assessment domains.Figure 8.4 Example of mnemonics used for assessment of pain.Figure 8.5 Example of non‐pharmacological management strategies.Figure 8.6 Classifications of pharmacological analgesics (examples).Figure 8.7 Analgesic ladder.Figure 8.8 Additional equipment that may be required.
8 Chapter 9Figure 9.1 Bacteria.Figure 9.2 Sites of action of different types of antibiotic agent. DNA, PABA...
9 Chapter 10Figure 10.1 Coronary artery disease.Figure 10.2 (a) The conducting system of the heart. (b) Normal electrical co...Figure 10.3 Clinical picture of cardiac failure.
10 Chapter 11Figure 11.1 The internal structure of the kidney and the nephron.Figure 11.2 KDIGO (2012) classification of CKD.Figure 11.3 The adverse effects of certain drugs upon the kidney.Figure 11.4 Site of diuretic effects upon the nephron.Figure 11.5 Distal convoluted tubule (DCT) cell and thiazide diuretic site o...Figure 11.6 The effects of aldosterone on the principal cells.Figure 11.7 The process of bicarbonate reabsorption in the proximal convolut...Figure 11.8 The effects of CKD upon phosphate and calcium metabolism.Figure 11.9 Sites of drug action upon urinary tract.Figure 11.10 α1 adrenoreceptor and the site of action of an α1 antagonist....Figure 11.11 Muscarinic (M1 and M3) receptor.
11 Chapter 12Figure 12.1 Pathophysiology related to abnormal glucose metabolism in type 2...Figure 12.2 The pancreas.Figure 12.3 Insulin – a two‐chain molecule.Figure 12.4 Some signs and symptoms of hypoglycaemia.Figure 12.5 How insulin and glucagon work to maintain blood glucose levels....
12 Chapter 13Figure 13.1 Macroscopic overview of upper and lower respiratory tract.Figu...Figure 13.2 Macroscopic overview of upper and lower respiratory tract. Mag...Figure 13.3 Macroscopic overview of upper and lower respiratory tract. Mag...Figure 13.4 Macroscopic overview of upper and lower respiratory tract. Mag...Figure 13.5 Nervous system control of respiratory airways.Figure 13.6 Structure of bronchial tissue during an asthma exacerbation.Figure 13.7 Pathophysiological triad of asthma.Figure 13.8 Normal peak expiratory flow rate measurements for age 15 years a...Figure 13.9 Pharmacological treatment pathway of asthma for adults aged 17 a...Figure 13.10 Chronic obstructive pulmonary disease.Figure 13.11 The pathophysiological cycle of bronchiectasis as originally pr...Figure 13.12 Non‐rebreathe mask.Figure 13.13 Simple facemask.Figure 13.14 Venturi valves.Figure 13.15 Nasal cannulae.Figure 13.16 Flow chart for titration of oxygen therapy.Figure 13.17 β2 adrenoceptor.Figure 13.18 Muscarinic (M3) receptor.Figure 13.19 β2 adrenoceptor and the site of action of Xanthines (PDE inhibi...Figure 13.20 Metered dose Inhaler.Figure 13.21 Spacer.Figure 13.22 Dry powder inhaler.Figure 13.23 Nebuliser.Figure 13.24 The hypothalamic–pituitary–adrenal (HPA) axis.Figure 13.25 The pharmacological effect of glucocorticoids.Figure 13.26 Mast cell granule contents and their effects.
13 Chapter 14Figure 14.1 Common sites for peptic ulcer.Figure 14.2 The large intestine.Figure 14.3 The Bristol stool chart.
14 Chapter 15Figure 15.1 Hallmarks of a cancer cell.Figure 15.2 The cell cycle.Figure 15.3 The immune system.Figure 15.4 Mononuclear antibodies.Figure 15.5 Cell activity with checkpoint inhibitor.Figure 15.6 Types of bone marrow transplant.
15 Chapter 16Figure 16.1 The imbalance of neurotransmitters in Parkinson's disease.Figure 16.2 Main drugs used in Parkinson's disease.Figure 16.3 Multiple sclerosis.Figure 16.4 Role of the MS specialist nurse.
16 c17Figure 17.1 Z‐track injection technique.
17 Chapter 18Figure 18.1 Types of immunity.Figure 18.2 A typical cold chain system.Figure 18.3 An example of a patient specific direction.Figure 18.4 Location of the deltoid muscle.Figure 18.5 Location of the rectus femoris and vastus lateralis muscles of t...
Guide
1 Cover
2 Table of Contents
Pages
1 iii
2 iv
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4 xxii
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