13.5 The pathophysiology of type 2 diabetes. The cardinal features ar...Figure 13.6 (a) Endogenous insulin secretion in type 2 diabetes and under no...Figure 13.7 Natural history of insulin resistance and insulin secretion in t...Figure 13.8 (a) Under normal physiological conditions, the renal tubule re‐a...Figure 13.9 The imperative for screening for type 2 diabetes. It is estimate...Figure 13.10 Main sites of action for antidiabetes agents. Different antidia...Figure 13.11 Ligand‐activated nuclear hormone receptors (review Chapter 3). ...Figure 13.12 Thiazolidinediones: mode of action. After the thiazolidinedione...Figure 13.13 How thiazolidinediones enhance insulin action and normalize blo...Figure 13.14 Actions of GLP‐1 and mode of action of DPP‐4 inhibitors and GLP...Figure 13.15 Gastrointestinal carbohydrate digestion and site of action of a...14 Chapter 14Figure 14.1 The chronic microvascular and macrovascular complications of dia...Figure 14.2 Effect of improved glycaemic management on diabetes (DM) related...Figure 14.3 Molecular mechanisms that may be important in the generation of ...Figure 14.4 Sorbitol Polyol Pathway. The normal function of aldose reductase...Figure 14.5 Retinal photographs reproduced with the kind permission of the U...Figure 14.6 A suggested plan for annual screening for kidney disease in diab...Figure 14.7 Algorithm for management of painful neuropathy in people with di...Figure 14.8 Plantar ulcer in a person with diabetes. Note how dry the skin a...Figure 14.9 Infected diabetic ulcer on the dorsum of the foot.Figure 14.10 (a) The combination of infection and vascular disease puts the ...Figure 14.11 Active Charcot arthropathy.Figure 14.12 Plantar ulcer in a patient with diabetes whose foot has become ...
15 Chapter 15Figure 15.1 The global prevalence of obesity in 2016.Figure 15.2 All‐cause mortality versus BMI for men and women in the range 15...Figure 15.3 Model of regulation of food intake. Appetite is stimulated by ne...Figure 15.4 What is a successful outcome?Figure 15.5 Rationale of 500 kcal deficit diet.Figure 15.6 Additive effects of diet and drugs.
Guide
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2 Table of Contents
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