Pet-Specific Care for the Veterinary Team. Группа авторов

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gluconate, chlorhexidine digluconate, calcium chloride admixed with dimethyl sulfoxide, etc

       mechanical castration, using ultrasound to induce testicular necrosis

       vaccinations against LH and GnRH, spermatozoa, or zona pellucida proteins

       melatonin implants.

      Toblerone is a 1‐year‐old intact female Great Dane that presents to you for elective surgical sterilization. Given the breed's predisposition to gastric‐dilation volvulus (GDV), the client is interested in prophylactic gastropexy at the time of OVH. However, he worries about intraoperative hemorrhage and the large incision. You indicate that there is an alternative to the traditional laparotomy that is required to perform both procedures. You suggest that the patient undergoes laparoscopic OVE and gastropexy.

       Pet overpopulation is a global, multifaceted, animal welfare issue.

       Sterilization surgery is considered the standard of care in the US as a means of population control.

       Early‐age gonadectomy is increasingly common given that safe anesthetic protocols have been developed.

       The desire for less invasive procedures has led to the successful adoption of OVE in other countries.

       Research is growing in the area of reversible contraception.

      2.18.7 Cautions

      Gonadectomy is not without risk. Surgical complication rates vary from study to study; however, as many as 6.1–27% of bitches and 2.6–33% of queens experience postoperative complications [9, 33].

      Obesity is common among neutered dogs and cats [6, 10]. In addition, neutered dogs are at greater risk of developing:

       prostatic neoplasia [6]

       transitional cell carcinoma (TCC) [34, 35]

       osteosarcoma [36, 37]

       cranial cruciate ligament rupture (CCLR) [14].

      Timing of gonadectomy may also influence a patient's predisposition to orthopedic disease [6, 14]. A recent study of 1842 dogs suggests that dogs neutered before 5 months of age have an increased incidence of hip dysplasia [4, 14].

      Interest in reversible contraceptive methods continues to build but its efficacy and the potential for adverse effects remain concerns.

      1 1 Farnworth, M.J., Adams, N.J., Seksel, K. et al. (2013). Veterinary attitudes towards pre‐pubertal gonadectomy of cats: a comparison of samples from New Zealand, Australia and the United Kingdom. N. Z. Vet. J. 61: 226–233.

      2 2 Pet Statistics. (2019). www.aspca.org/animal‐homelessness/shelter‐intake‐and‐surrender/pet‐statistics

      3 3 Asa, C.S. (2018). Contraception in dogs and cats. Vet. Clin. North Am. Small Anim. Pract. 48: 733–742.

      4 4 Spain, C.V., Scarlett, J.M., and Houpt, K.A. (2004). Long‐term risks and benefits of early‐age gonadectomy in dogs. J. Am. Vet. Med. Assoc. 224: 380–387.

      5 5 Lieberman, L.L. (1987). A case for neutering pups and kittens at two months of age. J. Am. Vet. Med. Assoc. 191: 518–521.

      6 6 Kustritz, M.V.R. (2007). Determining the optimal age for gonadectomy of dogs and cats. J. Am. Vet. Med. Assoc. 231: 1665–1675.

      7 7 Alexander, S.A. and Shane, S.M. (1994). Characteristics of animals adopted from an animal control center whose owners complied with a spaying/neutering program. J. Am. Vet. Med. Assoc. 205: 472–476.

      8 8 Spain, C.V., Scarlett, J.M., and Cully, S.M. (2002). When to neuter dogs and cats: a survey of New York state veterinarians' practices and beliefs. J. Am. Anim. Hosp. Assoc. 38: 482–488.

      9 9 Kustritz, M.V.R. (2014). Pros, cons, and techniques of pediatric neutering. Vet. Clin. North Am. Small Anim. Pract. 44: 221–233.

      10 10 Reichler, I.M. (2009). Gonadectomy in cats and dogs: a review of risks and benefits. Reprod. Domest. Anim. 44: 29–35.

      11 11 Schneider, R., Dorn, C.R., and Taylor, D.O. (1969). Factors influencing canine mammary cancer development and postsurgical survival. J. Natl. Cancer Inst. 43: 1249–1261.

      12 12 Hayes, H.M. Jr., Milne, K.L., and Mandell, C.P. (1981). Epidemiological features of feline mammary carcinoma. Vet. Rec. 108: 476–479.

      13 13 Misdorp, W. (1988). Canine mammary tumours: protective effect of late ovariectomy and stimulating effect of progestins. Vet. Q. 10: 26–33.

      14 14 Reichler, I.M. (2009). Gonadectomy in cats and dogs: a review of risks and benefits. Reprod. Domest. Anim. 44 (Suppl 2): 29–35.

      15 15 Kustritz, M.V.R. (1996). Elective gonadectomy in the cat. Feline Pract. 24: 36–39.

      16 16 Faggella, A.M. and Aronsohn, M.G. (1994). Evaluation of anesthetic protocols for neutering 6‐ to 14‐week‐old pups. J. Am. Vet. Med. Assoc. 205: 308–314.

      17 17 Howe, L.M. (1997). Short‐term results and complications of prepubertal gonadectomy in cats and dogs. J. Am. Vet. Med. Assoc. 211: 57–62.

      18 18 van Goethem, B., Schaefers‐Okkens, A., and Kirpensteijn, J. (2006). Making a rational choice between ovariectomy and ovariohysterectomy in the dog: a discussion of the benefits of either technique. Vet. Surg. 35: 136–143.

      19 19 DeTora, M. and McCarthy, R.J. (2011). Ovariohysterectomy versus ovariectomy for elective sterilization of female dogs and cats: is removal of the uterus necessary? J. Am. Vet. Med. Assoc. 239: 1409–1412.

      20 20 Salmeri, K.R., Bloomberg, M.S., Scruggs, S.L. et al. (1991). Gonadectomy in immature dogs: effects on skeletal, physical, and behavioral development. J. Am. Vet. Med. Assoc. 198: 1193–1203.

      21 21 Goericke‐Pesch, S. (2010). Reproduction control in cats: new developments in non‐surgical methods. J. Feline Med. Surg. 12: 539–546.

      22 22 Agudelo, C.F. (2005). Cystic endometrial hyperplasia‐pyometra complex in cats. A review. Vet. Q. 27: 173–182.

      23 23 Volpe, P., Izzo, B., Russo, M. et al. (2001). Intrauterine device for contraception in dogs. Vet. Rec. 149: 77–79.

      24 24 Wiebe, V.J. and Howard, J.P. (2009). Pharmacologic advances in canine and feline reproduction. Top. Compan. Anim. Med. 24: 71–99.

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