Protein in Neonatal and Infant Nutrition: Recent Updates. Группа авторов
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Rahul Jagdishlal Verma/India
Alaql Fahad Abdulrahman/Saudi Arabia
Sulaiman Alsaad/Kuwait
Pei Fan Chai/Malaysia
Dagoberto Delgado/Mexico
Otilia Perichart/Mexico
Salvador Villalpando/Mexico
Huma Fahim/Pakistan
Elizabeth Gallardo/Philippines
Gracia Paliza/Philippines
Mercedes Puya Sagarbarria/Philippines
Maria Josephine Sunga/Philippines
Elena Lukushkina/Russian Federation
Sergey Ukraintsev/Russian Federation
Marion Aw/Singapore
Rachel Yip Choy Har/Singapore
Kenny Ee/Singapore
Poh Choo Khoo/Singapore
Lin Min, Lena Kong/Singapore
Fung Chi, Angelin Lin/Singapore
Whati Lindiwe/Singapore
Winston Ng/Singapore
Victor Samuel Rajadurai/Singapore
Nancy Tan/Singapore
Vanessa Tan/Singapore
Janice Wong/Singapore
Fabian Yap/Singapore
Yeng Yoong Yip/Singapore
Peter Erdmann/Switzerland
Sanjeev Ganguly/Switzerland
Anette Järvi/Switzerland
Evelyn Spivey-Krobath/Switzerland
Simona Stan/Switzerland
Shih-Ming Chu/Taiwan/China
Beng-Huat Lau/Taiwan/China
Eva Peng/Taiwan/China
Po-Nien Tsao/Taiwan/China
Mei-Li Wang/Taiwan/China
Meng-Che Wu/Taiwan/China
San-Nan Yang/Taiwan/China
Chun-Yan Yeung/Taiwan/China
Pantipa Chatchatee/Thailand
Nalinee Chongviriyaphan/Thailand
Narumon Densupsoontorn/Thailand
Narissara Suratannon/Thailand
Turgay Coskun/Turkey
Karin Harput/Turkey
Hatice Serap Sivri/Turkey
Rasit Vural Yagci/Turkey
86th Nestlé Nutrition Institute Workshop
Beijing, May 24-27, 2015
Hydrolyzed Protein in Infant Feeding
Bhatia J, Shamir R, Vandenplas Y (eds): Protein in Neonatal and Infant Nutrition: Recent Updates.
Nestlé Nutr Inst Workshop Ser, vol 86, pp 1-10, (DOI: 10.1159/000442697)
Nestec Ltd., Vevey/S. Karger AG., Basel, © 2016
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Proteins, Peptides and Amino Acids: Role in Infant Nutrition
Sophie Nutten
Nutrition and Health Research Department, Nestlé Research Center, Lausanne, Switzerland
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Abstract
Proteins are polymers composed of 30 or more amino acids; some of them are essential dietary components, since they are not synthetized by human metabolic processes. They are crucial for healthy growth and development and influence major functions of the body. The infant’s first year is a critical time of rapid growth and development, which must be supported by a high rate of protein synthesis. Breast milk, as a single specific food source in the first months of life, is providing the total protein and essential amino acids required. Infant formulas have been designed for infants who cannot be breastfed. They should be similar to breast milk in their composition and their functional outcomes, insuring appropriate growth, optimal development, maturation of the immune system, easy digestion and healthy metabolic programming. By modifying their protein components, specific infant formulas have also been developed for specific needs. For example, partially hydrolyzed (prevention of atopic dermatitis) and extensively hydrolyzed or amino-acid-based infant formulas (reduction in allergy symptoms) have been designed for the management of cow’s milk protein allergy. In conclusion, proteins provided via breast milk or infant formula are essential components of the infant’s diet; therefore, the specific quality, quantity and conformation of proteins are of utmost importance for healthy growth and development.
© 2016 Nestec Ltd., Vevey/S. Karger AG, Basel
Proteins, Peptides and Amino Acids: Definitions
Proteins, from the Greek proetios (meaning ‘first’), are a fundamental component for life. They are the second most abundant chemical compound in the body after water. Following digestion, dietary proteins are absorbed as amino acids, which then contribute to the total amino acid pool, from which the body’s proteins are synthetized. Proteins are the main building blocks of the body and are involved in maintaining numerous body functions, in repairing or replacing cells or tissues, and in growth.
Table 1. Essential and nonessential amino acids
Nonessential amino acids (can be synthetized by the human body) | Conditionally essential amino acids (can be synthetized by the human body except in certain conditions) | Essential amino acids (cannot be synthetized by the human body; must be supplied through nutrition) |
Alanine | Arginine | Histidine |
Aspartate | Asparagine |