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Email: [email protected]
2
Ibero-American Network as a Collaborative Strategy to Provide Tools for the Development of Phytopharmaceuticals and Nutraceuticals
Pilar Buera1*, Cecilia Abirached2, Liliana Alamilla-Beltrán3, Verónica María Busch1, Cristina Isabel dos Santos1, Abel Farroni4, Leonardo Cristian Favre1, Aldo Fernández-Varela5, Fabiano Freire-Costa6, Julieta Gabilondo7, Micaela Galante8, María Eugenia Hidalgo8, Romina Ingrassia8,10, Milagros López Hiriart8,10, Alejandra Medrano2, Oscar Micheloni11, Miguel Navarro Alarcón12, Luis Panizzolo2, Silvia del Carmen Pereyra-Castro3, Viridiana Pérez-Pérez3, Carla Patricia Plazola-Jacinto3, Patricia Risso8,10, Paz Robert-Canales9, Analía Rodriguez2, Silvio David Rodríguez1, Erick Rojas-Balcazar13, José Angel Rufián Henares12 and Franco Emanuel Vasile14
1CONICET–Universidad de Buenos Aires, Instituto de Tecnología de Alimentos y Procesos Químicos (ITAPROQ), Buenos Aires, Argentina
2Facultad de Química, Universidad de la República, Montevideo, Uruguay
3Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México, Mexico
4Estación Experimental Agropecuaria Pergamino (EEA Pergamino), Instituto Nacional de Tecnología Agropecuaria (INTA), Pergamino, Argentina
5Universidad Popular del César, y Fundación para la Ciencia y la Agroindustria Tropical Tropilogía, Valledupar, Colombia
6Departamento de Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal de Juiz de Fora, Minas Gerais, Brazil
7Instituto Nacional de Tecnología Agropecuaria, Estación Experimental San Pedro, San Pedro, Argentina
8Departamento de Química-Física, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario and CONICET, Rosario, Argentina
9Departamento de Ciencia de los Alimentos y Tecnología Química, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago, Chile
10Facultad de Ciencias Veterinarias, Universidad Nacional de Rosario, Casilda, Argentina
11Departamento de Ciencias Básicas, Escuela de Ciencias Agrarias y Naturales, Universidad Nacional del Noroeste de la Provincia de Buenos Aires, Pergamino, Argentina
12Departamento de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Granada, Granada, Spain
13Universidad Autónoma Gabriel René Moreno, Santa Cruz, Bolivia
14Universidad Nacional del Chaco Austral, Presidencia Roque Sáenz Peña, Chaco, Argentina
Abstract
The increasing trend for using natural ingredients for nutraceuticals and phytopharmaceuticals development triggers the study of non-traditional sources for phytopharmaceuticals development, such as underexploited plants and agroindustrial wastes. The extraction, characterization and stabilization of bioactive compounds are intricate due to their low concentrations and their complex interactions in the vegetable matrix. New simple, ecological and efficient technologies are being developed to overcome the disadvantages of traditional extraction procedures, and many strategies should be developed to preserve their bioactivity. Oxidative reactions and protein glycation are two of the main deteriorative reactions affecting biological molecules and functionality loss in vitro and in vivo. Thus, efforts have been extended in search of edible plants with antioxidant or antiglycant properties. This chapter is an outcome of the CYTED Iberoamerican network 415RT0495, which task was to promote the valorization of subvaluated sources of bioactive compounds for food and medical uses.
Keywords: Bioactive natural compounds, edible
