or anthropology, or Old Testament history, the principal theoretical constructions always include features which no appeal to present or to accessible future experience can ever definitely test. Hence the suspicion with which students of experimental science often regard the theoretical constructions of their confrères of the sciences that deal with the past. The origin of the races of men, of man himself, of life, of species, of the planet; the hypotheses of anthropologists, of archeologists, of students of 'higher criticism'—all these are matters which the men of the laboratory often regard with a general incredulity as belonging not at all to the domain of true science. Yet no one can doubt the importance and the inevitableness of endeavoring to apply scientific method to these regions also. Science needs theories regarding the past history of the world. And no one who looks closer into the methods of these sciences of past time can doubt that verifiable and unverifiable hypotheses are in all these regions inevitably interwoven; so that, while experience is always the guide, the attitude of the investigator towards experience is determined by interests which have to be partially due to what I should call that 'internal meaning,' that human interest in rational theoretical construction which inspires the scientific inquiry; and the theoretical constructions which prevail in such sciences are neither unbiased reports of the actual constitution of an external reality, nor yet arbitrary constructions of fancy. These constructions in fact resemble in a measure those which M. Poincaré in this book has analyzed in the case of geometry. They are constructions molded, but not predetermined in their details, by experience. We report facts; we let the facts speak; but we, as we investigate, in the popular phrase, 'talk back' to the facts. We interpret as well as report. Man is not merely made for science, but science is made for man. It expresses his deepest intellectual needs, as well as his careful observations. It is an effort to bring internal meanings into harmony with external verifications. It attempts therefore to control, as well as to submit, to conceive with rational unity, as well as to accept data. Its arts are those directed towards self-possession as well as towards an imitation of the outer reality which we find. It seeks therefore a disciplined freedom of thought. The discipline is as essential as the freedom; but the latter has also its place. The theories of science are human, as well as objective, internally rational, as well as (when that is possible) subject to external tests.
In a field very different from that of the historical sciences, namely, in a science of observation and of experiment, which is at the same time an organic science, I have been led in the course of some study of the history of certain researches to notice the existence of a theoretical conception which has proved extremely fruitful in guiding research, but which apparently resembles in a measure the type of hypotheses of which M. Poincaré speaks when he characterizes the principles of mechanics and of the theory of energy. I venture to call attention here to this conception, which seems to me to illustrate M. Poincaré's view of the functions of hypothesis in scientific work.
The modern science of pathology is usually regarded as dating from the earlier researches of Virchow, whose 'Cellular Pathology' was the outcome of a very careful and elaborate induction. Virchow, himself, felt a strong aversion to mere speculation. He endeavored to keep close to observation, and to relieve medical science from the control of fantastic theories, such as those of the Naturphilosophen had been. Yet Virchow's researches were, as early as 1847, or still earlier, already under the guidance of a theoretical presupposition which he himself states as follows: "We have learned to recognize," he says, "that diseases are not autonomous organisms, that they are no entities that have entered into the body, that they are no parasites which take root in the body, but that they merely show us the course of the vital processes under altered conditions" ('dasz sie nur Ablauf der Lebenserscheinungen unter veränderten Bedingungen darstellen').
The enormous importance of this theoretical presupposition for all the early successes of modern pathological investigation is generally recognized by the experts. I do not doubt this opinion. It appears to be a commonplace of the history of this science. But in Virchow's later years this very presupposition seemed to some of his contemporaries to be called in question by the successes of recent bacteriology. The question arose whether the theoretical foundations of Virchow's pathology had not been set aside. And in fact the theory of the parasitical origin of a vast number of diseased conditions has indeed come upon an empirical basis to be generally recognized. Yet to the end of his own career Virchow stoutly maintained that in all its essential significance his own fundamental principle remained quite untouched by the newer discoveries. And, as a fact, this view could indeed be maintained. For if diseases proved to be the consequences of the presence of parasites, the diseases themselves, so far as they belonged to the diseased organism, were still not the parasites, but were, as before, the reaction of the organism to the veränderte Bedingungen which the presence of the parasites entailed. So Virchow could well insist. And if the famous principle in question is only stated with sufficient generality, it amounts simply to saying that if a disease involves a change in an organism, and if this change is subject to law at all, then the nature of the organism and the reaction of the organism to whatever it is which causes the disease must be understood in case the disease is to be understood.
For this very reason, however, Virchow's theoretical principle in its most general form could be neither confirmed nor refuted by experience. It would remain empirically irrefutable, so far as I can see, even if we should learn that the devil was the true cause of all diseases. For the devil himself would then simply predetermine the veränderte Bedingungen to which the diseased organism would be reacting. Let bullets or bacteria, poisons or compressed air, or the devil be the Bedingungen to which a diseased organism reacts, the postulate that Virchow states in the passage just quoted will remain irrefutable, if only this postulate be interpreted to meet the case. For the principle in question merely says that whatever entity it may be, bullet, or poison, or devil, that affects the organism, the disease is not that entity, but is the resulting alteration in the process of the organism.
I insist, then, that this principle of Virchow's is no trial supposition, no scientific hypothesis in the narrower sense—capable of being submitted to precise empirical tests. It is, on the contrary, a very precious leading idea, a theoretical interpretation of phenomena, in the light of which observations are to be made—'a regulative principle' of research. It is equivalent to a resolution to search for those detailed connections which link the processes of disease to the normal process of the organism. Such a search undertakes to find the true unity, whatever that may prove to be, wherein the pathological and the normal processes are linked. Now without some such leading idea, the cellular pathology itself could never have been reached; because the empirical facts in question would never have been observed. Hence this principle of Virchow's was indispensable to the growth of his science. Yet it was not a verifiable and not a refutable hypothesis. One value of unverifiable and irrefutable hypotheses of this type lies, then, in the sort of empirical inquiries which they initiate, inspire, organize and guide. In these inquiries hypotheses in the narrower sense, that is, trial propositions which are to be submitted to definite empirical control, are indeed everywhere present. And the use of the other sort of principles lies wholly in their application to experience. Yet without what I have just proposed to call the 'leading ideas' of a science, that is, its principles of an unverifiable and irrefutable character, suggested, but not to be finally tested, by experience, the hypotheses in the narrower sense would lack that guidance which, as M. Poincaré has shown, the larger ideas of science give to empirical investigation.
V
I have dwelt, no doubt, at too great length upon one aspect only of our author's varied and well-balanced discussion of the problems and concepts of scientific theory. Of the hypotheses in the narrower sense and of the value of direct empirical control, he has also spoken with the authority and the originality which belong to his position. And in dealing with the foundations of mathematics he has raised one or two questions of great philosophical import into which I have no time, even if I had the right, to enter here. In particular, in speaking of the essence of mathematical reasoning, and of the difficult problem of what makes possible novel results in the field of pure mathematics, M. Poincaré defends a thesis regarding the office of 'demonstration by recurrence'—a thesis which is indeed
