Secondary Metabolites of Medicinal Plants. Bharat Singh

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Secondary Metabolites of Medicinal Plants - Bharat Singh

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of azadirachtin in neem cell cultures (Satdive et al. 2007).

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      5 Anuradha, V.E., Jaleel, C.A., Salem, M.A. et al. (2010). Plant growth regulators induced changes in antioxidant potential and andrographolide content in Andrographis paniculata Wall. ex Nees. Pestic. Biochem. Physiol. 98: 312–316.

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      12 Ekong, D.E.U. (1967). Chemistry of the meliacins (limonoids). The structure of nimbolide, a new meliacin from Azadirachta indica. Chem. Commun. (London) 1967: 808a.

      13 Festucci-Buselli, R.A., Contim, L.A.S., Barbosa, L.C.A. et al. (2008). Biosynthesis and potential functions of the ecdysteroid 20-hydroxyecdysone – a review. Can. J. Bot. 86: 978–987.

      14 Fulzele, D.P. and Satdive, R.K. (2001). Growth and production of camptothecin by cell suspension cultures of Nothapodytes foetida. Planta Med. 67: 150–152.

      15 Govindachari, T.R. and Gopalakrishnan, G. (1997). 13,14-desepoxy-azadirachtin-A, a tetranortriterpenoid from Azadirachta indica. Phytochemistry 45: 397–399.

      16 Govindachari, T.R., Sandhya, G., and Ganeshraj, S.P. (1992). Structure of azadirachtin-K, a new tetranortriterpenoid from Azadirachta indica. Indian J. Chem. 31B: 295–298.

      17 Govindachari, T.R., Narasimhan, N.S., Suresh, G. et al. (1996a). Insect antifeedant and growth-regulating activities of Salannin and other C-seco limonoids from neem oil in relation to Azadirachtin. J. Chem. Ecol. 22: 1453–1461.

      18 Govindachari, T.R., Gopalakrishnan, G., and Suresh, G. (1996b). Isolation of various azadirachtins from neem oil by preparative high performance liquid chromatography. J. Liq. Chromatogr. Related Technol. 19: 1729–1733.

      19 Govindachari, T.R., Gopalakrishnan, G., and Suresh, G. (1997). Purification of azadirachtin-B(3-tigloylazadirachtol) by preparative high performance liquid chromatography, using the recycling mode. J. Liq. Chromatogr. Related Technol. 20: 1633–1636.

      20 Govindachari, T.R., Suresh, G., Gopalakrishnan, G., and Wesley, S.D. (2000). Insect antifeedant and growth regulating activities of neem seed oil – the role of major tetranortriterpenoids. J. Appl. Entomol. 124: 287–291.

      21 Haque, E., Mandal, I., Pal, S., and Baral, R. (2006). Prophylactic dose of neem (Azadirachta indica) leaf preparation restricting murine tumor growth is nontoxic, hematostimulatory and immunostimulatory. Immunopharmacol. Immunotoxicol. 28: 33–50.

      22 Hossain, M.A., Al-Toubi, W.A.S., Weli, A.M. et al. (2013). Identification and characterization of chemical compounds in different crude extracts from leaves of Omani neem. J. Taibah Univ. Sci. 7: 181–188.

      23 Jadeja, G.C., Maheshwari, R.C., and Naik, S.N. (2011). Extraction of natural insecticide azadirachtin from neem (Azadirachta indica A. Juss) seed kernels using pressurized hot solvent. J. Supercrit. Fluids 56: 253–258.

      24 Jarvis, A.P. and Morgan, E.D. (2000). Analysis of small samples of limonoids of neem (Azadirachta indica) using solid phase extraction from tissue culture. Phytochem. Anal. 11: 184–189.

      25 Kaii-a-Kamb, M., Amoral, M., and Girr, L. (1992). Search for new antiviral agents of plant origin. Pharm. Acta Helv. 67: 130–147.

      26 Kota, S., Rao, N.D.R., and Chary, P. (2006). In vitro response of select regions of Azadirachta indica A. Juss (Meliaceae) as elucidated by biochemical and molecular variations. Curr. Sci. 91: 770–776.

      27 Kuruvilla, T., Komariah, P., and Ramakrishna, S.V. (1999). Enhanced secretion of azadirachtin by permeabilized margosa (Azadirachta indica) cells. Indian J. Exp. Biol. 37: 89–91.

      28 Mordue, A.J. and Nisbet, A.J. (2000). Azadirachtin from the neem tree Azadirachta indica: its action against insects. An. Soc. Entomol. Bras. 29: 615–632.

      29 Nagella, P. and Murthy, H.N. (2010). Establishment of cell suspension cultures of Withania somnifera for the production of withanolide A. Bioresour. Technol. 101: 6735–6739.

      30 Nakabayashi, R., Yamazaki, M., and Saito, K. (2010). A polyhedral approach for understanding flavonoid biosynthesis in Arabidopsis. New Biotechnol. 27: 829–836.

      31 Poornasri Devi, B., Vimala, A., Sai, I., and Chandra, S. (2008). Effect of cyanobacterial elicitor on neem cell suspension cultures. Indian J. Sci. Technol. 1: 1–6.

      32 Prakash, G. and Srivastava, A.K. (2005). Statistical media optimization for cell growth and azadirachtin production in Azadirachta indica (A. Juss) suspension cultures. Process Biochem. 40: 3795–3800.

      33 Prakash, G. and Srivastava, A.K. (2006). Modeling of azadirachtin production by Azadirachta indica and its use for feed forward optimization studies. Biochem. Eng. J. 29: 62–68.

      34 Prakash, G., Bhojwani, S.S., and Srivastava, A.K. (2002). Production of azadirachtin from plant tissue culture – state of the art and future prospects. Biotechnol. Bioprocess Eng. 7: 185–193.

      35 Rafiq, M. and Dahot, M.U. (2010). Callus and azadirachtin related limonoids production through in vitro culture of neem (Azadirachta indica A. Juss). Afr. J. Biotechnol. 9: 449–453.

      36 Raval, N.K., Hellwig, S., Prakash, G. et al. (2003). Necessity of a two-stage process for the production of azadirachtin-related limonoids in suspension cultures of Azadirachta indica. J. Biosci. Bioeng. 96: 16–22.

      37 Rodrigues, M., Festucci-Buselli, R.A., Silva, L.C., and Otoni, W.C.

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