Principles of Virology, Volume 2. S. Jane Flint

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DNA Advisory Committee.

      Vincent R. Racaniello is Higgins Professor of Microbiology & Immunology at Columbia University Vagelos College of Physicians & Surgeons. Dr. Racaniello has been studying viruses for over 40 years, including poliovirus, rhinovirus, enteroviruses, hepatitis C virus, and Zika virus. He teaches virology to undergraduate, graduate, medical, dental, and nursing students and uses social media to communicate the subject outside of the classroom. His Columbia University undergraduate virology lectures have been viewed by thousands at iTunes University, Coursera, and on YouTube. Vincent blogs about viruses at virology.ws and is host of the popular science program This Week in Virology, which, together with six other science podcasts, can be found at microbe.tv.

      Glenn F. Rall is a Professor and the Chief Academic Officer at the Fox Chase Cancer Center in Philadelphia. He is an Adjunct Professor in the Microbiology and Immunology departments at the University of Pennsylvania and Thomas Jefferson, Drexel, and Temple Universities. Dr. Rall’s laboratory studies viral infections of the brain and the immune responses to those infections, with the goal of defining how viruses contribute to disease in humans. His service to the scientific community includes former membership on the Autism Speaks Scientific Advisory Board, Editor of PLoS Pathogens, Career Development Chair and Program Chair of the American Society for Virology, and membership on multiple NIH grant review panels.

      Anna Marie Skalka is a Professor Emerita and former Senior Vice President for Basic Research at the Fox Chase Cancer Center in Philadelphia. Dr. Skalka’s major research interests are the molecular aspects of retrovirus biology. Dr. Skalka is internationally recognized for her contributions to the understanding of the biochemical mechanisms by which such viruses (including the AIDS virus) replicate and insert their genetic material into the host genome. Both an administrator and researcher, Dr. Skalka has been deeply involved in state, national, and international advisory groups concerned with the broader, societal implications of scientific research. She has also served on the editorial boards of peer-reviewed scientific journals and has been a member of scientific advisory boards including the National Cancer Institute Board of Scientific Counselors, the General Motors Cancer Research Foundation Awards Assembly, the Board of Governors of the American Academy of Microbiology, and the National Advisory Committee for the Pew Biomedical Scholars.

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        Introduction to Viral Pathogenesis

        A Brief History of Viral Pathogenesis The Relationships among Microbes and the Diseases They Cause The First Human Viruses Identified and the Role of Serendipity New Methods Facilitate the Study of Viruses as Causes of Disease

        Viral Epidemics in History Epidemics Shaped History: the 1793 Yellow Fever Epidemic in Philadelphia Tracking Epidemics by Sequencing: West Nile Virus Spread to the Western Hemisphere Zoonotic Infections and Epidemics Caused by “New” Viruses The Economic Toll of Viral Epidemics in Livestock Population Density and World Travel Are Accelerators of Viral Transmission Focus on Frontline Health Care: Ebolavirus in Africa Emergence of a Birth Defect Associated with Infection: Zika Virus in Brazil

        Epidemiology Fundamental Concepts Methods Used by Epidemiologists Surveillance Network Theory and Practical Applications

        Parameters That Govern the Ability of a Virus to Infect a Population Geography and Population Density Climate

        Perspectives

        References

        Study Questions

      LINKS FOR CHAPTER 1

       Video: Interview with Dr. W. Thomas London http://bit.ly/Virology_London

       Epidemiology causes conclusions (p less than 0.01) http://bit.ly/Virology_Twiv169

       Slow motion sneezing http://bit.ly/Virology_1-23-13

       CD4 Hunter http://bit.ly/Virology_Twiv489

      HANS ZINSSER

      Rats, Lice and History, 1934

      While

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