Practical Cardiovascular Medicine. Elias B. Hanna

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TREATMENT OF HEART FAILURE 1. TREATMENT OF SYSTOLIC HEART FAILURE I. Treat the underlying etiology: target BP and CAD II. Value of revascularization in ischemic cardiomyopathy: STICH trial III. Role of viability testing and ischemic testing IV. Drugs that affect survival in EF<40% V. Specifics of drugs that affect survival VI. Drugs that improve symptoms and morbidity VII. Devices VIII. Other therapeutic measures IX. Prognosis 2. TREATMENT OF HFPEF ACUTE HEART FAILURE AND ACUTELY DECOMPENSATED HEART FAILURE I. Triggers of acute decompensation II. Profiles of acute HF: congestion without low cardiac output, congestion with low cardiac output III. Treatment of acute HF: diagnosis and treatment of triggers IV. Treatment of acute HF: diuretics, cardiorenal syndrome, aggressive decongestion, ultrafiltration V. Treatment of acute HF: vasodilators VI. Treatment of acute HF: IV inotropic agents VII. In-hospital and pre-discharge use of ACE-I/ARB, angiotensin-neprilysin inhibition, and β-blockers VIII. Treatment of acute HF: O2, non-invasive ventilatory support (CPAP, BiPAP), intubation IX. Summary: keys to the treatment of acute HF (Table 4.2) X. Discharge XI. Inability of severe HF to tolerate vasodilatation or hemodialysis XII. Outpatient monitoring of HF and prevention of hospitalization Appendix 1. Management of isolated or predominant RV failure QUESTIONS AND ANSWERS References Diuretics 5 Additional Heart Failure Topics 1. SPECIFIC CARDIOMYOPATHIES 2. ADVANCED HEART FAILURE: HEART TRANSPLANT AND VENTRICULAR ASSIST DEVICES (VADs) 3. PATHOPHYSIOLOGY OF HEART FAILURE AND HEMODYNAMIC ASPECTS QUESTIONS AND ANSWERS References

      10  Part 3: VALVULAR DISORDERS 6 Valvular Disorders 1. MITRAL REGURGITATION 2. MITRAL STENOSIS 3. AORTIC INSUFFICIENCY 4. AORTIC STENOSIS 5. TRICUSPID REGURGITATION AND STENOSIS 6. PULMONIC STENOSIS AND REGURGITATION 7. MIXED VALVULAR DISEASE; RADIATION HEART DISEASE 8. PROSTHETIC VALVES 9. AUSCULTATION AND SUMMARY IDEAS QUESTIONS AND ANSWERS References

      11  Part 4: HYPERTROPHIC CARDIOMYOPATHY 7 Hypertrophic Cardiomyopathy QUESTIONS AND ANSWERS References

      12  Part 5: ARRHYTHMIAS AND ELECTROPHYSIOLOGY 8 Approach to Narrow and Wide QRS Complex Tachyarrhythmias Further reading 9 Ventricular Arrhythmias QUESTIONS AND ANSWERS References 10 Atrial Fibrillation I. Predisposing factors (see Table 10.1) II. Types of AF III. General therapy of AF IV. Management of a patient who presents with acute, symptomatic AF V. Peri-cardioversion anticoagulation management VI. Antiarrhythmic management after the acute presentation VII. Decisions about long-term anticoagulation, role of clopidogrel, role of triple therapy VIII. Special situation: atrial fibrillation and heart failure. Optimal heart rate in heart failure IX. Special situation: atrial fibrillation with borderline blood pressure or non-AF-related hypotension X. AF burden as a correlate and a driver of HF progression Appendix 1. Optimal heart rate and AF rate for optimal cardiac output Appendix 2. Antiarrhythmic drug therapy

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