Historical Overview and Definitions of Concepts
32.2 Areas of Industrial Application of Molecular Biotechnology
32.3 Status Quo of the Biotech Industry Worldwide
33 Patents in the Molecular Biotechnology Industry: Legal and Ethical Issues
33.1 Patent Law
33.2 Ethical and Policy Issues in Biotechnology Patents
33.3 Conclusions
Acknowledgments
34 Drug Approval in the European Union and United States
34.1 Introduction
34.2 Regulation Within the European Union
34.3 Regulation in the United States
34.4 The Advent and Regulation of Biosimilars
34.5 International Regulatory Harmonization
References
35 Emergence of a Biotechnology Industry
Reference
Further Reading
36 The 101 of Founding a Biotech Company
36.1 First Steps Toward Your Own Company
36.2 Employees: Recruitment, Remuneration, and Participation
37 Marketing
37.1 Introduction
37.2 What Types of Deals Are Possible?
37.3 What Milestone or License Fees Are Effectively Paid in a Biotech/Pharma Cooperation?
37.4 PR and IR in Biotech Companies
Further Reading
Websites
9 Glossary
10 Index
List of Tables
1 Chapter 1Table 1.1 Comparison of important biochemical and molecular characteristics o...Table 1.2 Compartments of animal and plant cells and their main functions.Table 1.3 Important methodological tools of modern biology.
2 Chapter 2Table 2.1 Molecular composition of cells.Table 2.2 Formation and function of the cellular macromolecules.Table 2.3 Important fatty acids in membrane lipids.Table 2.4 Compilation and grouping of the proteinogenic amino acids: two type...Table 2.5 Important classes of enzymes.Table 2.6 Many vitamins serve as essential coenzymes for enzyme reactions.Table 2.7 Nomenclature of DNA and RNA building blocks.Table 2.8 Enzymes that use DNA as a substrate and are used in genetic enginee...
3 Chapter 3Table 3.1 Ion concentrations inside mammalian cells and in the extracellular ...Table 3.2 Most important hormones in humans.Table 3.3 The role of adenylyl cyclase and phospholipase C‐β in signal ...Table 3.4 Some functions of trimeric G‐proteins.Table 3.5 Signal proteins that act via receptor tyrosine kinases.Table 3.6 Prokaryotic properties of plastids and mitochondria.Table 3.7 Classification of major animal and human pathogenic viruses.Table 3.8 Viral oncogenes that may play a part in the emergence of tumors.Table 3.9 Overview of important cell types in plants and animals.
4 Chapter 4Table 4.1 Overview of a few of the genomes that are already sequenced and pub...Table 4.2 Relation between genome size and the number of genes of a few selec...Table 4.3 A few characteristics of the human genome.Table 4.4 Spontaneous DNA damage in a single diploid mammalian cell within 24...Table 4.5 Genetic diseases, which are associated with defective DNA repair sy...Table 4.6 Consensus sequences in eukaryotic promoter regions.Table 4.7 Protein biosynthesis in bacterial ribosomes as a target for antibio...
5 Chapter 5Table 5.1 Examples of typical recognition sequences.Table 5.2 Occurrence of some Rab proteins.
6 Chapter 6Table 6.1 Important groups of protists (model organisms or diseases caused by...Table 6.2 Systematic classification of the land plants.Table 6.3 Systematic classification of multicellular animals (important phyla...
